Dirhodium-Catalyzed [2 + 2 + 2] Cycloaddition of 1,6-Diynes and Alkynes

IF 3.6 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2024-11-08 DOI:10.1021/acs.joc.4c01780

Xiang Gao, Wendeng Li, Yang Chen, Rui Wu, Shifa Zhu

引用次数: 0

Abstract

A facile method for the construction of fused arenes has been developed through dirhodium-catalyzed [2 + 2 + 2] cycloaddition, which represents a new application of dirhodium complexes. This protocol is convenient to handle without the addition of extra ligands and reductants and tolerates a broad range of functional groups. Mechanistic studies revealed that the two-electron oxidation process, carboxylate ligand departure, and heteroatom coordination-promoted [2 + 2 + 2] cycloaddition were possibly involved.

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二氢铑催化 1,6-二炔和炔烃的 [2 + 2 + 2] 环加成反应

通过二铑催化的[2 + 2 + 2]环化反应，我们开发出了一种构建融合烯烃的简便方法，这代表了二铑配合物的一种新应用。这种方法无需添加额外的配体和还原剂，操作简便，可容忍多种官能团。机理研究表明，其中可能涉及双电子氧化过程、羧酸配体离去和杂原子配位促进的 [2 + 2 + 2] 环加成反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.