Estelle Sabourin , Clémentine De La Porte des Vaux , Nathanaël Veluppillai , Marie-Elisabeth Bougnoux , Eric Dannaoui , Olivier Lortholary
{"title":"Case report: Candida blankii osteo-articular infection in a patient with Chronic Granulomatous Disease","authors":"Estelle Sabourin , Clémentine De La Porte des Vaux , Nathanaël Veluppillai , Marie-Elisabeth Bougnoux , Eric Dannaoui , Olivier Lortholary","doi":"10.1016/j.mmcr.2024.100682","DOIUrl":null,"url":null,"abstract":"<div><div><em>Candida blankii</em> is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical <em>C. blankii</em> metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease. The patient was initially treated by a combination of voriconazole and 5-fluorocytosine (5-FC). However, the treatment was subsequently changed to posaconazole and then to a combination of caspofungin and 5-FC.</div><div>2012 Elsevier Ltd. All rights reserved.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100682"},"PeriodicalIF":1.6000,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753924000563","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Candida blankii is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical C. blankii metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease. The patient was initially treated by a combination of voriconazole and 5-fluorocytosine (5-FC). However, the treatment was subsequently changed to posaconazole and then to a combination of caspofungin and 5-FC.