[Severe coronavirus-2 infection background for cardiovascular complications].

Juan Angel Cibrian-Delgado, Maraí Xóchitl Gutiérrez-Galván, Agustin Ramiro Urzua-Gonzalez, Sadia Huallpa-Rodríguez, Martha A Hernandez-Gonzale
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Abstract

Background: Covid-19 infection can affect the cardiovascular system in the long term, due to the inflammation and endothelial damage caused by SARS-CoV-2. It is unknown whether patients who have had severe covid-19 have a higher risk of cardiovascular complications than those who have not.

Objective: To compare the presentation of cardiovascular complications in patients with a history of severe SARS-CoV-2 infection and population without this history.

Material and methods: An observational analytical cohort study was conducted that included 988 patients, with a calculation for the sample size to detect a minimum RR of 1.5 with a statistical power of 80%. The outcome was measured through electronic medical records and variables were compared. A descriptive analysis was performed using measures of central tendency and dispersion for quantitative variables and absolute and relative frequencies for qualitative variables.

Results: The history of severe covid-19 infection is related to a higher risk of rehospitalization for cardiovascular causes. There was an increase in the frequency of endocarditis, arrhythmias and thrombotic events. Type 4a infarcts and thrombi in the right atrium were more common in patients with covid-19.

Conclusions: Covid-19 was associated with a higher hospital readmission for cardiac problems, such as endocarditis and arrhythmias. A persistent negative impact on long-term cardiovascular health was identified in these patients.

[心血管并发症的严重冠状病毒-2 感染背景]。
背景:由于SARS-CoV-2引起的炎症和内皮损伤,Covid-19感染可长期影响心血管系统。目前尚不清楚感染过严重的 Covid-19 的患者是否比未感染过 Covid-19 的患者有更高的心血管并发症风险:比较有严重 SARS-CoV-2 感染史的患者和无此病史的人群的心血管并发症表现:我们进行了一项观察性分析队列研究,共纳入 988 名患者,计算样本量的目的是在 80% 的统计能力下检测出最低 RR 值 1.5。研究结果通过电子病历进行测量,并对变量进行比较。对定量变量采用中心倾向和离散度量,对定性变量采用绝对频率和相对频率进行描述性分析:结果:有严重covid-19感染史的患者因心血管原因再次住院的风险较高。心内膜炎、心律失常和血栓事件的发生频率增加。4a型心梗和右心房血栓在感染Covid-19的患者中更为常见:结论:Covid-19 与心内膜炎和心律失常等心脏问题的再入院率较高有关。这些患者的长期心血管健康受到持续的负面影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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