Yun Song, Yaru Wang, Huafang Zhang, Muhammad Abu Bakar Saddique, Xiumei Luo, Maozhi Ren
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引用次数: 0
Abstract
Plant diseases caused by fungal phytopathogens have led to significant economic losses in agriculture worldwide. The management of fungal diseases is mainly dependent on the application of fungicides, which are not suitable for sustainable agriculture, human health, and environmental safety. Thus, it is necessary to develop novel targets and green strategies to mitigate the losses caused by these pathogens. The target of rapamycin (TOR) complexes and key components of the TOR signalling pathway are evolutionally conserved in pathogens and closely related to the vegetative growth and pathogenicity. As indicated in recent systems, chemical, genetic, and genomic studies on the TOR signalling pathway, phytopathogens with TOR dysfunctions show severe growth defects and nonpathogenicity, which makes the TOR signalling pathway to be developed into an ideal candidate target for controlling plant disease. In this review, we comprehensively discuss the current knowledge on components of the TOR signalling pathway in microorganisms and the diverse roles of various plant TOR in response to plant pathogens. Furthermore, we analyse a range of disease management strategies that rely on the TOR signalling pathway, including genetic modification technologies and chemical controls. In the future, disease control strategies based on the TOR signalling network are expected to become a highly effective weapon for crop protection.
由真菌植物病原体引起的植物病害给全球农业造成了巨大的经济损失。真菌病害的管理主要依赖于杀菌剂的应用,而杀菌剂并不适合可持续农业、人类健康和环境安全。因此,有必要开发新型靶标和绿色战略,以减轻这些病原体造成的损失。雷帕霉素靶标(TOR)复合物和 TOR 信号通路的关键组分在病原体中进化保守,与无性生殖和致病性密切相关。近年来关于 TOR 信号通路的系统、化学、遗传和基因组研究表明,TOR 功能失调的植物病原菌表现出严重的生长缺陷和非致病性,这使得 TOR 信号通路成为控制植物病害的理想候选靶标。在这篇综述中,我们全面讨论了微生物中 TOR 信号通路成分的现有知识,以及各种植物 TOR 在应对植物病原体时的不同作用。此外,我们还分析了一系列依赖于 TOR 信号通路的病害防治策略,包括基因修饰技术和化学防治。未来,基于 TOR 信号网络的病害控制策略有望成为作物保护的高效武器。
期刊介绍:
Molecular Plant Pathology is now an open access journal. Authors pay an article processing charge to publish in the journal and all articles will be freely available to anyone. BSPP members will be granted a 20% discount on article charges. The Editorial focus and policy of the journal has not be changed and the editorial team will continue to apply the same rigorous standards of peer review and acceptance criteria.