Clinical and Radiographic Features of Peri-Implant Medication-Related Osteonecrosis of the Jaw: A Retrospective Study.

Hyeon-Gyu Jo, Wonse Park, In-Ho Cha, Young-Soo Jung, Da Yun Lee, Jun-Young Kim
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Abstract

Introduction: This study aimed to analyze the factors affecting the occurrence of peri-implant medication-related osteonecrosis of the jaw (PI-MRONJ) in patients using anti-resorptive drugs (ARDs) on different implant position, inclinations, and types of prosthesis.

Methods: The data of 75 patients with bone necrosis that progressed around the implant between 2018 and 2022 were retrospectively examined to identify the factors influencing PI-MRONJ. Data, including patient demographics (age, sex, smoking status, concomitant disease, time of ARD therapy, dose of ARDs, and parafunctional habits) and implant-specific information (type of prosthesis, angle of insertion), were extracted from medical and dental records.

Results: Tilted implants with an angle ≥ 5.1° relative to the occlusal plane of the prosthesis had a stronger association with PI-MRONJ in comparison to non-tilted implants (inclination was < 5°). Additionally, the boundary of the area of osteonecrosis around the fixture was larger for the splinted implant-supported crowns than for the single implant supported crowns).

Conclusion: In patients taking anti-resorptive medications the inclination of the implant was associated with the occurrence of PI-MRONJ. Further studies are required to confirm the clinical findings.

植入前药物相关性颌骨骨坏死的临床和放射学特征:一项回顾性研究
导言:该研究旨在分析在不同种植体位置、倾斜度和修复体类型上使用抗吸收药物(ARDs)的患者发生种植体周围药物相关性颌骨坏死(PI-MRONJ)的影响因素:回顾性研究了2018年至2022年间75例种植体周围骨坏死进展患者的数据,以确定影响PI-MRONJ的因素。数据包括患者人口统计学特征(年龄、性别、吸烟状况、伴随疾病、ARD治疗时间、ARD剂量和副功能习惯)和种植体特定信息(修复体类型、插入角度),均从医疗和牙科记录中提取:结果:与非倾斜种植体相比,相对于修复体咬合面角度≥5.1°的倾斜种植体与PI-MRONJ的关系更为密切(倾斜度为5.1°):在服用抗骨质吸收药物的患者中,种植体的倾斜度与 PI-MRONJ 的发生有关。需要进一步的研究来证实临床发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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