Periodontitis Is Associated With Arterial Stiffness as Measured by Serial Cardio-Ankle Vascular Index (CAVI): A 10-Year Cohort Study.

IF 5.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Clinical Periodontology Pub Date : 2024-11-06 DOI:10.1111/jcpe.14086

Bantita Kanpittaya, Attawood Lertpimonchai, Sanutm Mongkornkarn, Lakshman Samaranayake, Nisakorn Thongmung, Thosaphol Limpijankit, Orawan Charatkulangkun

{"title":"Periodontitis Is Associated With Arterial Stiffness as Measured by Serial Cardio-Ankle Vascular Index (CAVI): A 10-Year Cohort Study.","authors":"Bantita Kanpittaya, Attawood Lertpimonchai, Sanutm Mongkornkarn, Lakshman Samaranayake, Nisakorn Thongmung, Thosaphol Limpijankit, Orawan Charatkulangkun","doi":"10.1111/jcpe.14086","DOIUrl":null,"url":null,"abstract":"Aim: To investigate the effect of periodontitis on the long-term changes of the cardio-ankle vascular index (CAVI).Materials and methods: A 10-year retrospective cohort study of 3842 Thai participants (range 25-76 years) with normal CAVI at the study initiation was undertaken. Full-mouth periodontal examination was performed by calibrated periodontists, and the extent and severity of periodontitis were determined at 5-year intervals. Serial CAVI measurements were used to examine the incidence of high CAVI (≥ 9.0) and changes in CAVI over time (ΔCAVI).Results: Participants with a higher extent or severity of periodontitis were found to have a significantly higher mean ΔCAVI. The incidence of high CAVI was also observed to be higher in those with periodontitis compared to those without it. The adjusted risk ratios for developing high CAVI were 1.309 and 1.513 for localized and generalized periodontitis, respectively. Participants with severe periodontitis had a 37% higher likelihood of developing CAVI ≥ 9.0 compared to individuals with no/mild periodontitis. This risk was consistent with a significant change in ΔCAVI of 0.054-0.140.Conclusions: Periodontitis, both in terms of extent and severity, was found to have a significant dose-dependent effect on the risk of developing high CAVI over a 10-year period, suggesting a causal relationship between these two parameters.","PeriodicalId":15380,"journal":{"name":"Journal of Clinical Periodontology","volume":" ","pages":""},"PeriodicalIF":5.8000,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Periodontology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/jcpe.14086","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Aim: To investigate the effect of periodontitis on the long-term changes of the cardio-ankle vascular index (CAVI).

Materials and methods: A 10-year retrospective cohort study of 3842 Thai participants (range 25-76 years) with normal CAVI at the study initiation was undertaken. Full-mouth periodontal examination was performed by calibrated periodontists, and the extent and severity of periodontitis were determined at 5-year intervals. Serial CAVI measurements were used to examine the incidence of high CAVI (≥ 9.0) and changes in CAVI over time (ΔCAVI).

Results: Participants with a higher extent or severity of periodontitis were found to have a significantly higher mean ΔCAVI. The incidence of high CAVI was also observed to be higher in those with periodontitis compared to those without it. The adjusted risk ratios for developing high CAVI were 1.309 and 1.513 for localized and generalized periodontitis, respectively. Participants with severe periodontitis had a 37% higher likelihood of developing CAVI ≥ 9.0 compared to individuals with no/mild periodontitis. This risk was consistent with a significant change in ΔCAVI of 0.054-0.140.

Conclusions: Periodontitis, both in terms of extent and severity, was found to have a significant dose-dependent effect on the risk of developing high CAVI over a 10-year period, suggesting a causal relationship between these two parameters.

查看原文本刊更多论文

牙周炎与动脉僵化有关，可通过序列心-踝血管指数（CAVI）测量：一项为期 10 年的队列研究

目的：研究牙周炎对心踝血管指数（CAVI）长期变化的影响：对 3842 名泰国参试者（年龄在 25-76 岁之间）进行了为期 10 年的回顾性队列研究，这些参试者在研究开始时的心踝关节血管指数均正常。由经过校准的牙周病学家进行全口牙周检查，每隔 5 年确定牙周炎的范围和严重程度。连续的 CAVI 测量用于检查高 CAVI（≥ 9.0）的发生率和 CAVI 随时间的变化（ΔCAVI）：结果：发现牙周炎范围或严重程度较高的参与者的平均 ΔCAVI 明显较高。此外，还观察到牙周炎患者的高 CAVI 发生率高于无牙周炎患者。局部性牙周炎和全身性牙周炎发生高 CAVI 的调整风险比分别为 1.309 和 1.513。与无牙周炎/轻度牙周炎患者相比，患有重度牙周炎的患者发生 CAVI ≥ 9.0 的可能性要高出 37%。这一风险与ΔCAVI 0.054-0.140 的显著变化相一致：结论：研究发现，牙周炎的范围和严重程度对 10 年内罹患高 CAVI 的风险具有显著的剂量依赖性，这表明这两个参数之间存在因果关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Clinical Periodontology 医学-牙科与口腔外科

CiteScore

13.30

自引率

10.40%

发文量

175

审稿时长

3-8 weeks

期刊介绍： Journal of Clinical Periodontology was founded by the British, Dutch, French, German, Scandinavian, and Swiss Societies of Periodontology. The aim of the Journal of Clinical Periodontology is to provide the platform for exchange of scientific and clinical progress in the field of Periodontology and allied disciplines, and to do so at the highest possible level. The Journal also aims to facilitate the application of new scientific knowledge to the daily practice of the concerned disciplines and addresses both practicing clinicians and academics. The Journal is the official publication of the European Federation of Periodontology but wishes to retain its international scope. The Journal publishes original contributions of high scientific merit in the fields of periodontology and implant dentistry. Its scope encompasses the physiology and pathology of the periodontium, the tissue integration of dental implants, the biology and the modulation of periodontal and alveolar bone healing and regeneration, diagnosis, epidemiology, prevention and therapy of periodontal disease, the clinical aspects of tooth replacement with dental implants, and the comprehensive rehabilitation of the periodontal patient. Review articles by experts on new developments in basic and applied periodontal science and associated dental disciplines, advances in periodontal or implant techniques and procedures, and case reports which illustrate important new information are also welcome.