High-frequency wearable ultrasound array belt for small animal echocardiography.

IF 3 2区 工程技术 Q1 ACOUSTICS
Yushun Zeng, Xin Sun, Junhang Zhang, Chi-Feng Chang, Baoqiang Liu, Chen Gong, Jie Ji, Bryan Zhen Zhang, Yujie Wang, Matthew Xinhu Ren, Robert Wodnicki, Hsiao-Chuan Liu, Qifa Zhou
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引用次数: 0

Abstract

Wearable ultrasound has been widely developed for long-term, continuous imaging without the need for bulky system manipulation and repeated manual locating. To potentially lead to more accurate and reliable imaging monitoring, this work presents the design, fabrication, and evaluation of a novel high-frequency wearable ultrasound array belt (WUAB) for small animal echocardiography. The fabrication process involved precise dicing technology for a λ-pitch design. The 20 MHz WUAB consists of two matching layers, piezoelectric composite with 128 channels, customized flexible circuit substrate, acoustic backing layer, and customized belt structure with designed end tip and insertion point for wearability. The resulting WUAB demonstrates sensitivity of -5.69 ± 2.5 dB and fractional bandwidth of 57 ± 5 %. In vivo experiments on rat model showed expected echocardiography and B-mode images of rat heart. These results represent significant promise for future longitudinal studies in small animals and real-time physiological monitoring.

用于小动物超声心动图的高频可穿戴式超声阵列腰带。
可穿戴超声设备已得到广泛开发,可用于长期、连续成像,而无需笨重的系统操作和重复的人工定位。为了实现更精确、更可靠的成像监测,这项工作介绍了一种用于小动物超声心动图的新型高频可穿戴超声阵列带(WUAB)的设计、制造和评估。制造过程采用精确切割技术,以实现 λ 间距设计。20 MHz WUAB 由两个匹配层、128 个通道的压电复合材料、定制的柔性电路基板、声学背层和定制的皮带结构组成,皮带末端和插入点经过设计,具有良好的耐磨性。WUAB 的灵敏度为 -5.69 ± 2.5 dB,分数带宽为 57 ± 5 %。在大鼠模型上进行的体内实验显示,大鼠心脏的超声心动图和 B 型图像达到预期效果。这些结果为今后在小动物中进行纵向研究和实时生理监测带来了巨大希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.70
自引率
16.70%
发文量
583
审稿时长
4.5 months
期刊介绍: IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control includes the theory, technology, materials, and applications relating to: (1) the generation, transmission, and detection of ultrasonic waves and related phenomena; (2) medical ultrasound, including hyperthermia, bioeffects, tissue characterization and imaging; (3) ferroelectric, piezoelectric, and piezomagnetic materials, including crystals, polycrystalline solids, films, polymers, and composites; (4) frequency control, timing and time distribution, including crystal oscillators and other means of classical frequency control, and atomic, molecular and laser frequency control standards. Areas of interest range from fundamental studies to the design and/or applications of devices and systems.
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