{"title":"A Case of Abnormal Elevation of Serum CA 72-4 Caused by Colchicine.","authors":"Gangfeng Li, Tao Lu","doi":"10.7754/Clin.Lab.2024.240601","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>CA 72-4 is a tumor associated antigen which shows significantly increased serum levels in gastric cancer. It is the most commonly used serum tumor marker for diagnosing symptomatic gastric cancer and monitoring gastric cancer treatment.</p><p><strong>Methods: </strong>We report the case of a gout patient with abnormal elevation of serum CA 72-4 caused by taking colchicine.</p><p><strong>Results: </strong>The patient's painless gastroscopy and other examinations showed no obvious abnormalities, and no detection interference was detected. After discontinuing treatment with colchicine, CA 72-4 level of the patient returned to normal. Therefore, the abnormal increase of CA 72-4 is believed to be caused by colchicine.</p><p><strong>Conclusions: </strong>When gout patients receive colchicine treatment, it may lead to an abnormal increase in CA 72-4 results. Laboratory staff should consider the existence of such interference and promptly remind clinical doctors to avoid unnecessary examination and treatment of patients.</p>","PeriodicalId":10384,"journal":{"name":"Clinical laboratory","volume":"70 11","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical laboratory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7754/Clin.Lab.2024.240601","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: CA 72-4 is a tumor associated antigen which shows significantly increased serum levels in gastric cancer. It is the most commonly used serum tumor marker for diagnosing symptomatic gastric cancer and monitoring gastric cancer treatment.
Methods: We report the case of a gout patient with abnormal elevation of serum CA 72-4 caused by taking colchicine.
Results: The patient's painless gastroscopy and other examinations showed no obvious abnormalities, and no detection interference was detected. After discontinuing treatment with colchicine, CA 72-4 level of the patient returned to normal. Therefore, the abnormal increase of CA 72-4 is believed to be caused by colchicine.
Conclusions: When gout patients receive colchicine treatment, it may lead to an abnormal increase in CA 72-4 results. Laboratory staff should consider the existence of such interference and promptly remind clinical doctors to avoid unnecessary examination and treatment of patients.
期刊介绍：
Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.
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