Associations among frailty conditions and pain indicators: Data from 22 356 European older adults

IF 2.4 4区医学 Q3 GERIATRICS & GERONTOLOGY

Geriatrics & Gerontology International Pub Date : 2024-11-06 DOI:10.1111/ggi.15016

Trinidad Sentandreu-Mañó, Elena Marques-Sule, Pallav Deka, José M Tomás, Leiver Andrés Romero Pintado, Leonie Klompstra, Hady Atef

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引用次数: 0

Abstract

Aim

Recent studies supported the presence of a relationship between pain and frailty, but more research is needed to highlight the pain–frailty association. The study aimed to investigate the prevalence and the influence of different pain indicators on frailty while controlling for age, sex and country.

Methods

This observational study used data from the sixth wave of the SHARE survey. A sample of 22 356 community-dwelling individuals aged >60 years from six European countries (Spain, Estonia, France, Greece, Czech Republic and Sweden) was analyzed. The pain was measured through assessment of medication used for joint pain or other types of pain, pain location, polypharmacy and pain level. Frailty was assessed with the modified Fried Frailty phenotype.

Results

Pain indicators, especially widespread pain and pain severity, were significantly associated with prefrailty (odds ratio 3.30, 95% CI 2.40, 4.55; and odds ratio 0.61, 95% CI 0.51, 0.72) and frailty status (odds ratio 4.69, 95% CI 3.31, 6.67; and odds ratio 0.37, 95% CI 0.30, 0.44). Advancing age and female sex consistently correlated with increased prefrailty (odds ratio 1.06, 95% CI 1.05, 1.07; and odds ratio 1.36, 95% CI 1.22, 1.53) and frailty risk (odds ratio 1.11, 95% CI 1.10, 1.12; and odds ratio 1.71, 95% CI 1.48, 1.96). Country-specific differences emerged, with Spaniards showing higher odds ratios of prefrailty and frailty compared with Swedish, French and Czech individuals, whereas Greeks showed elevated odds ratios compared with Spaniards. The factors associated jointly explained 27.5% of the variance in frailty categories.

Conclusion

Significant associations were identified, particularly with widespread pain and pain severity, highlighting their impact on frailty. Country-specific variations in frailty prevalence were observed, alongside consistent associations with advancing age and female sex. These findings provide valuable insights into the intricate interplay between pain and frailty, offering the potential for targeted interventions in older adults' care through tailored pain management strategies. Geriatr Gerontol Int 2024; 24: 1362–1369.

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虚弱状况与疼痛指标之间的关联：22 356 名欧洲老年人的数据。

目的：最近的研究证实疼痛与虚弱之间存在关系，但还需要更多的研究来强调疼痛与虚弱之间的关系。本研究旨在调查不同疼痛指标的发生率及其对虚弱的影响，同时控制年龄、性别和国家：这项观察性研究使用了 SHARE 调查第六波的数据。研究分析了来自六个欧洲国家（西班牙、爱沙尼亚、法国、希腊、捷克共和国和瑞典）的 22 356 名年龄大于 60 岁的社区居民样本。通过评估关节疼痛或其他类型疼痛的用药情况、疼痛部位、多重用药情况和疼痛程度来测量疼痛。通过改良弗里德虚弱表型对虚弱程度进行评估：结果：疼痛指标，尤其是广泛性疼痛和疼痛严重程度，与虚弱前状态（几率比 3.30，95% CI 2.40，4.55；几率比 0.61，95% CI 0.51，0.72）和虚弱状态（几率比 4.69，95% CI 3.31，6.67；几率比 0.37，95% CI 0.30，0.44）显著相关。年龄的增长和女性性别与虚弱前期（几率比 1.06，95% CI 1.05，1.07；几率比 1.36，95% CI 1.22，1.53）和虚弱风险（几率比 1.11，95% CI 1.10，1.12；几率比 1.71，95% CI 1.48，1.96）的增加持续相关。不同国家之间存在差异，与瑞典、法国和捷克人相比，西班牙人显示出更高的虚弱前期和虚弱的几率比，而与西班牙人相比，希腊人显示出更高的几率比。相关因素共同解释了 27.5% 的虚弱类别差异：结论：研究发现了一些重要的关联因素，尤其是与广泛性疼痛和疼痛严重程度有关的因素，这些因素对虚弱的影响尤为突出。不同国家的虚弱患病率存在差异，同时与年龄增长和女性性别也有关联。这些发现为了解疼痛与虚弱之间错综复杂的相互作用提供了宝贵的见解，为通过量身定制的疼痛管理策略对老年人进行有针对性的干预提供了可能性。Geriatr Gerontol Int --; --：-----.Geriatr Gerontol Int 2024; --：-----.

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来源期刊

Geriatrics & Gerontology International 医学-老年医学

CiteScore

5.50

自引率

6.10%

发文量

189

审稿时长

4-8 weeks

期刊介绍： Geriatrics & Gerontology International is the official Journal of the Japan Geriatrics Society, reflecting the growing importance of the subject area in developed economies and their particular significance to a country like Japan with a large aging population. Geriatrics & Gerontology International is now an international publication with contributions from around the world and published four times per year.