A novel zein/Auricularia cornea Ehrenb polysaccharides coated quercetin nanocarrier: Characterization, stability, antioxidant activity, and bioaccessibility

IF 4.9 2区化学 Q2 CHEMISTRY, PHYSICAL

Colloids and Surfaces A: Physicochemical and Engineering Aspects Pub Date : 2024-10-29 DOI:10.1016/j.colsurfa.2024.135680

Wei Wang , Yan Cui , Xu Liu , Mingzhu Zheng , Yuhua Wang , Jingsheng Liu , Huimin Liu

{"title":"A novel zein/Auricularia cornea Ehrenb polysaccharides coated quercetin nanocarrier: Characterization, stability, antioxidant activity, and bioaccessibility","authors":"Wei Wang , Yan Cui , Xu Liu , Mingzhu Zheng , Yuhua Wang , Jingsheng Liu , Huimin Liu","doi":"10.1016/j.colsurfa.2024.135680","DOIUrl":null,"url":null,"abstract":"<div><div>This study aimed to develop a novel and stable delivery system based on zein and <em>Auricularia cornea</em> Ehrenb polysaccharides (ACEP) for quercetin (Que). The pH-driven self-assembly combined with electrostatic deposition methods were employed to construct zein-ACEP nanoparticles (ZA NPs). The optimized nanocomposite was prepared at zein: ACEP mass ratios of 3:2, and it had superior ionic strength stability (0–75 mM NaCl), thermal stability (80°C for 30 min), average diameter of 185.6 nm, zeta-potential of −42.8 mV, and Que encapsulation efficiency of 75.8 %. The assembly of composites was facilitated primarily by hydrophobic, hydrogen-bonding, and electrostatic interactions. Que encapsulated with ZA NPs exhibited superior light stability, stronger antioxidant activity, and bioaccessibility than Que. Additionally, ZA NPs showed sustainable release capacity, and Que release from nanoparticles is consistent with an anomalous (non-Fickian) transport dominated by skeleton erosion. These findings demonstrate that ZA NPs have potential applications as an effective and viable delivery system for Que in functional food fields.</div></div>","PeriodicalId":278,"journal":{"name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","volume":"705 ","pages":"Article 135680"},"PeriodicalIF":4.9000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0927775724025445","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 0

Abstract

This study aimed to develop a novel and stable delivery system based on zein and Auricularia cornea Ehrenb polysaccharides (ACEP) for quercetin (Que). The pH-driven self-assembly combined with electrostatic deposition methods were employed to construct zein-ACEP nanoparticles (ZA NPs). The optimized nanocomposite was prepared at zein: ACEP mass ratios of 3:2, and it had superior ionic strength stability (0–75 mM NaCl), thermal stability (80°C for 30 min), average diameter of 185.6 nm, zeta-potential of −42.8 mV, and Que encapsulation efficiency of 75.8 %. The assembly of composites was facilitated primarily by hydrophobic, hydrogen-bonding, and electrostatic interactions. Que encapsulated with ZA NPs exhibited superior light stability, stronger antioxidant activity, and bioaccessibility than Que. Additionally, ZA NPs showed sustainable release capacity, and Que release from nanoparticles is consistent with an anomalous (non-Fickian) transport dominated by skeleton erosion. These findings demonstrate that ZA NPs have potential applications as an effective and viable delivery system for Que in functional food fields.

查看原文本刊更多论文

一种新型玉米蛋白/耳廓菌角膜 Ehrenb 多糖包覆的槲皮素纳米载体：特性、稳定性、抗氧化活性和生物可及性

本研究旨在开发一种新颖稳定的槲皮素（Que）递送系统，该系统基于玉米蛋白和鸡眼多糖（ACEP）。该研究采用pH自组装结合静电沉积的方法构建了玉米蛋白-ACEP纳米颗粒（ZA NPs）。优化的纳米复合材料是在玉米蛋白-ACEP质量比为3:2的条件下制备的：它具有优异的离子强度稳定性（0-75 mM NaCl）和热稳定性（80°C 30 分钟），平均直径为 185.6 nm，zeta 电位为 -42.8 mV，阙包封效率为 75.8%。主要通过疏水、氢键和静电作用促进了复合材料的组装。与阙相比，ZA NPs 封装的阙具有更高的光稳定性、更强的抗氧化活性和生物可接受性。此外，ZA NPs 还具有可持续释放能力，阙从纳米颗粒中的释放与骨架侵蚀主导的反常（非费克）迁移一致。这些研究结果表明，ZA NPs 作为一种有效、可行的阙输送系统，在功能食品领域具有潜在的应用前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Colloids and Surfaces A: Physicochemical and Engineering Aspects 化学-物理化学

CiteScore

8.70

自引率

9.60%

发文量

2421

审稿时长

56 days

期刊介绍： Colloids and Surfaces A: Physicochemical and Engineering Aspects is an international journal devoted to the science underlying applications of colloids and interfacial phenomena. The journal aims at publishing high quality research papers featuring new materials or new insights into the role of colloid and interface science in (for example) food, energy, minerals processing, pharmaceuticals or the environment.