Association of Questionnaire-Assessed Fall Risk With Uncontrolled Blood Pressure and Therapeutic Inertia Among Older Adults.

IF 2.7 3区 医学 Q2 PERIPHERAL VASCULAR DISEASE
Journal of Clinical Hypertension Pub Date : 2025-01-01 Epub Date: 2024-11-05 DOI:10.1111/jch.14933
Grant T Hiura, Talar W Markossian, Beatrice D Probst, Katherine Habicht, Holly J Kramer
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Abstract

Therapeutic inertia (TI), or failure to escalate or initiate BP lowering medications when BP is uncontrolled, increases with advancing age and may in part be due to perceived fall risk. This study examined the association of a fall risk assessment, based on patient response to three questions administered by trained staff, with uncontrolled BP (≥140/90 mmHg) during a clinic visit and with TI during clinic visits with uncontrolled BP among 13 893 patients age ≥ 65 years corresponding to 41 122 primary care visits. Separate generalized linear mixed effects models were used to examine the association of fall risk (low, moderate, and high) with uncontrolled BP and with TI at a clinic visit after adjustment for demographics, comorbidities, and total number of visits. Baseline mean age was 73.0 years (standard deviation [SD] 5.6), 43.3% were men and questionnaire-assessed fall risk severity was low in 73.6%, moderate in 14.3%, and high in 12.2%. Compared to low fall risk, the adjusted odds of uncontrolled BP during a clinic visit were 0.97 (95% CI: 0.89, 1.06) and 0.90 (95% CI: 0.82, 0.98) with moderate and high fall risk, respectively. In contrast, adjusted odds of TI during a clinic visit with BP ≥ 140/90 mmHg was 1.16 (95% CI: 1.01, 1.34) and 1.30 (95% CI: 1.11, 1.52) with moderate and high fall risk, respectively, compared to low fall risk. These findings suggest that perceived fall risk severity may be one of several factors that influence hypertension management in older adults.

问卷评估的跌倒风险与老年人血压失控和治疗惰性的关系
治疗惰性(TI),即在血压未得到控制时未升级或启动降压药物治疗,会随着年龄的增长而增加,部分原因可能是由于患者认为存在跌倒风险。本研究研究了 13 893 名年龄≥ 65 岁的患者(对应于 41 122 次初级保健就诊)在就诊期间的跌倒风险评估与血压未控制(≥ 140/90 mmHg)之间的关系,以及与血压未控制就诊期间的 TI 之间的关系。在对人口统计学、合并症和就诊总次数进行调整后,分别使用广义线性混合效应模型来检验跌倒风险(低、中、高)与血压未控制以及门诊就诊时血压指数的关系。基线平均年龄为 73.0 岁(标准差 [SD] 5.6),43.3% 为男性,问卷评估的跌倒风险严重程度分别为低度(73.6%)、中度(14.3%)和高度(12.2%)。与低跌倒风险相比,中度和高度跌倒风险患者在就诊期间血压失控的调整几率分别为 0.97(95% CI:0.89,1.06)和 0.90(95% CI:0.82,0.98)。相比之下,与低跌倒风险相比,中度和高度跌倒风险患者在门诊就诊时血压≥ 140/90 mmHg 的调整后跌倒风险几率分别为 1.16 (95% CI: 1.01, 1.34) 和 1.30 (95% CI: 1.11, 1.52)。这些研究结果表明,跌倒风险的严重程度可能是影响老年人高血压管理的几个因素之一。
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来源期刊
Journal of Clinical Hypertension
Journal of Clinical Hypertension PERIPHERAL VASCULAR DISEASE-
CiteScore
5.80
自引率
7.10%
发文量
191
审稿时长
4-8 weeks
期刊介绍: The Journal of Clinical Hypertension is a peer-reviewed, monthly publication that serves internists, cardiologists, nephrologists, endocrinologists, hypertension specialists, primary care practitioners, pharmacists and all professionals interested in hypertension by providing objective, up-to-date information and practical recommendations on the full range of clinical aspects of hypertension. Commentaries and columns by experts in the field provide further insights into our original research articles as well as on major articles published elsewhere. Major guidelines for the management of hypertension are also an important feature of the Journal. Through its partnership with the World Hypertension League, JCH will include a new focus on hypertension and public health, including major policy issues, that features research and reviews related to disease characteristics and management at the population level.
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