Pulmonary melioidosis mimicking lung cancer: a diagnostic challenge.

IF 1.9 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-11-06 DOI:10.1093/trstmh/trae089

Xiaohong Yang, Zhuopeng Ying, Yuefu Zhan, Jianqiang Chen

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引用次数: 0

Abstract

Background: The overlapping clinical and radiographic features of pulmonary melioidosis and lung cancer present diagnostic challenges to healthcare providers in endemic settings.

Methods: We compared the clinical, laboratory and imaging characteristics of 19 pulmonary melioidosis cases with those of 15 cases of small cell lung cancer (SCLC) and 17 cases of non-small cell lung cancer (NSCLC).

Results: Compared with SCLC/NSCLC cases, those with pulmonary melioidosis were more likely to have diabetes, have fever, neutrophilia and leukocytosis on presentation (p<0.05). While certain CT imaging features were shared between pulmonary melioidosis and SCLC ('frozen mediastinum sign', 'vascular encasement sign'), extensive liquefactive necrosis, uneven ring-enhancement, circular lesions and 'air-bubble' signs were more commonly seen in pulmonary melioidosis cases than in those with SCLC/NSCLC (p<0.05).

Conclusions: Despite the similarities in presentation of pulmonary melioidosis, SCLC and NSCLC, several clinical, laboratory and imaging factors may help delineate these diagnoses and improve patient care.

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模仿肺癌的肺梅里埃病：诊断难题。

背景：肺梅里埃病和肺癌的临床和影像学特征相互重叠，这给医疗服务提供者的诊断带来了挑战：肺黄疽和肺癌的临床和影像学特征相互重叠，这给地方病流行地区的医疗服务提供者带来了诊断上的挑战：我们比较了19例肺部黄疽病例与15例小细胞肺癌（SCLC）和17例非小细胞肺癌（NSCLC）病例的临床、实验室和影像学特征：结果：与小细胞肺癌/非小细胞肺癌病例相比，肺肉芽肿病病例在发病时更可能患有糖尿病、发热、中性粒细胞增多症和白细胞增多症（p结论：尽管肺肉芽肿病与小细胞肺癌/非小细胞肺癌病例的表现相似，但肺肉芽肿病病例在发病时更可能患有糖尿病、发热、中性粒细胞增多症和白细胞增多症：尽管肺肉芽肿病、SCLC 和 NSCLC 在表现形式上有相似之处，但一些临床、实验室和影像学因素可能有助于区分这些诊断并改善患者护理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.00

自引率

9.10%

发文量

115

审稿时长

4-8 weeks

期刊介绍： Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.