Clonal distribution and molecular characterization of Staphylococcus aureus isolated strains in Chania and Heraklion, Crete.

Q2 Medicine
Medicine and Pharmacy Reports Pub Date : 2024-10-01 Epub Date: 2024-10-30 DOI:10.15386/mpr-2783
Eftychios Vittorakis, Mihaela Laura Vica, Stanca-Lucia Pandrea, Amanda Rădulescu, Calina Oana Zervaki, Evangelos Vittorakis, Sofia Maraki, Viktoria Eirini Mavromanolaki, Michael Ewald Schürger, Vlad Sever Neculicioiu, Evangelia Papadomanolaki, Lia Monica Junie
{"title":"Clonal distribution and molecular characterization of <i>Staphylococcus aureus</i> isolated strains in Chania and Heraklion, Crete.","authors":"Eftychios Vittorakis, Mihaela Laura Vica, Stanca-Lucia Pandrea, Amanda Rădulescu, Calina Oana Zervaki, Evangelos Vittorakis, Sofia Maraki, Viktoria Eirini Mavromanolaki, Michael Ewald Schürger, Vlad Sever Neculicioiu, Evangelia Papadomanolaki, Lia Monica Junie","doi":"10.15386/mpr-2783","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of <i>Staphylococcus aureus</i> infections.</p><p><strong>Methods: </strong>The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.</p><p><strong>Results: </strong>The highest infection prevalence observed in the older adults (≥65 years) age group. The predominant infection types were skin lesions (39.72) and respiratory tract infection (22.7%). Antibiotic resistance testing revealed that 57.44% of strains were <i>MRSA</i>, with high resistance to Tetracycline, Ciprofloxacin, Kanamycine Erythromycin and Clindamycin. Molecular analysis showed 19.14% of strains were <i>Pvl</i>-positive, highlighting the presence of both <i>MRSA</i> and <i>MSSA</i> strains with <i>Pvl</i> genes.</p><p><strong>Conclusions: </strong>The study underscores the need for continuous surveillance and targeted infection control strategies to manage the spread of <i>MRSA</i>, particularly in vulnerable populations.</p>","PeriodicalId":18438,"journal":{"name":"Medicine and Pharmacy Reports","volume":"97 4","pages":"456-466"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534380/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine and Pharmacy Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15386/mpr-2783","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/30 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Aim: This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of Staphylococcus aureus infections.

Methods: The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.

Results: The highest infection prevalence observed in the older adults (≥65 years) age group. The predominant infection types were skin lesions (39.72) and respiratory tract infection (22.7%). Antibiotic resistance testing revealed that 57.44% of strains were MRSA, with high resistance to Tetracycline, Ciprofloxacin, Kanamycine Erythromycin and Clindamycin. Molecular analysis showed 19.14% of strains were Pvl-positive, highlighting the presence of both MRSA and MSSA strains with Pvl genes.

Conclusions: The study underscores the need for continuous surveillance and targeted infection control strategies to manage the spread of MRSA, particularly in vulnerable populations.

克里特岛夏尼亚和伊拉克利翁金黄色葡萄球菌分离菌株的克隆分布和分子特征。
目的:本研究调查了金黄色葡萄球菌感染的人口分布、抗生素耐药性概况和分子特征:研究对象是来自克里特岛夏尼亚和伊拉克利翁的 141 名患者,其中 60.4% 为男性:结果:老年人(≥65 岁)的感染率最高。主要感染类型为皮肤损伤(39.72%)和呼吸道感染(22.7%)。抗生素耐药性检测显示,57.44%的菌株为 MRSA,对四环素、环丙沙星、卡那霉素、红霉素和克林霉素的耐药性较高。分子分析显示 19.14% 的菌株 Pvl 阳性,这表明 MRSA 和 MSSA 菌株中都存在 Pvl 基因:这项研究强调了持续监测和有针对性的感染控制策略的必要性,以控制 MRSA 的传播,尤其是在易感人群中的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Medicine and Pharmacy Reports
Medicine and Pharmacy Reports Medicine-Medicine (all)
CiteScore
3.10
自引率
0.00%
发文量
63
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信