Clinical characteristics and outcomes of critically ill COVID-19 patients with CAUTI: a study in Vietnam.

IF 1.4 4区 医学 Q4 INFECTIOUS DISEASES
Dao Vu Do, Thi Hai Van Pham, Sam Nguyen, Thi Tuyet Mai Nguyen, Xuan Co Dao
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引用次数: 0

Abstract

Introduction: Urethral catheterization is commonly required in coronavirus disease 2019 (COVID-19) patients hospitalized in intensive care units (ICUs). However, this increases their vulnerability to nosocomial infections such as catheter-associated urinary tract infections (CAUTIs). Existing studies on nosocomial infections in COVID-19 patients usually report CAUTI prevalence but neglect the clinical differences between CAUTI and non-CAUTI patients. This study aimed to assess clinical features, microbiological characteristics, and outcomes of COVID-19 patients with CAUTI vs non-CAUTI patients in an ICU.

Methodology: We analyzed the clinical data from a retrospective cohort study of 527 critically ill COVID-19 patients who required urethral catheterization at the ICU of Bach Mai hospital in Ho Chi Minh City, Vietnam, from August to October 2021. A total of 69 patients (n = 37 CAUTI vs n = 32 non-CAUTI) were selected for urine culture, and their clinical features, microbiological characteristics, and outcomes were recorded for analysis.

Results: COVID-19 patients with CAUTI had a higher mortality rate compared to those without CAUTI (p = 0.02). The length of stay in the ICU was 1.4 times longer for CAUTI patients compared to the non-CAUTI group (p = 0.03). Fungi was the most common microbiological cause of UTI in COVID-19 ICU (91.4%), and Pseudomonas aeruginosa was a significant risk factor of CAUTI. P. aeruginosa, number of antibiotics used, and duration of catheterization had a strong association with the patients' survival time in ICU.

Conclusions: This study provides a better understanding of CAUTI in COVID-19 patients, thus facilitating their future treatment.

COVID-19 重症患者 CAUTI 的临床特征和预后:越南的一项研究。
导言:在重症监护病房(ICU)住院的 2019 年冠状病毒病(COVID-19)患者通常需要进行尿道导管插入术。然而,这增加了他们对导尿管相关尿路感染(CAUTIs)等院内感染的易感性。现有关于 COVID-19 患者院内感染的研究通常会报告 CAUTI 感染率,但忽略了 CAUTI 患者与非 CAUTI 患者之间的临床差异。本研究旨在评估重症监护病房中COVID-19型CAUTI患者与非CAUTI患者的临床特征、微生物学特征和预后:我们分析了一项回顾性队列研究的临床数据,研究对象是 2021 年 8 月至 10 月期间在越南胡志明市 Bach Mai 医院 ICU 需要进行尿道导管插入术的 527 例 COVID-19 重症患者。共选取了69名患者(n = 37 CAUTI vs n = 32 non-CAUTI)进行尿液培养,并记录分析了他们的临床特征、微生物学特征和结果:结果:COVID-19 CAUTI患者的死亡率高于非CAUTI患者(P = 0.02)。CAUTI患者在重症监护室的住院时间是非CAUTI组的1.4倍(p = 0.03)。真菌是 COVID-19 ICU 中最常见的 UTI 微生物病因(91.4%),铜绿假单胞菌是 CAUTI 的重要风险因素。铜绿假单胞菌、抗生素使用次数和导尿时间与患者在重症监护室的存活时间密切相关:本研究有助于更好地了解 COVID-19 患者的 CAUTI,从而为今后的治疗提供帮助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
5.30%
发文量
239
审稿时长
4-8 weeks
期刊介绍: The Journal of Infection in Developing Countries (JIDC) is an international journal, intended for the publication of scientific articles from Developing Countries by scientists from Developing Countries. JIDC is an independent, on-line publication with an international editorial board. JIDC is open access with no cost to view or download articles and reasonable cost for publication of research artcles, making JIDC easily availiable to scientists from resource restricted regions.
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