Extracorporeal membrane oxygenation in obstetrical patients: a meta-analysis.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-11-05 DOI:10.1007/s10047-024-01480-w

Wentao Bian, Shuang Liu, Ping Zhou, Kangling Yan, Jiancheng Zhang, Wenkai Bian, Qiang Zhang, Lu Ding

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Abstract

Critically acute and ill and Obstetrical patients constitute a unique clinical population with a high mortality rate. Extracorporeal membrane oxygenation (ECMO) is gradually being used in obstetrical acute and critically ill patients and has shown great advantages. PubMed, Embase, Web of Science, Chinese CNKI Database, and Cochrane Library databases were systematically searched from the earliest available date to March 15, 2024, to obtain relevant studies on extracorporeal membrane oxygenation in obstetric patients. After screening the literature, data were independently extracted and summarized using random effects or fixed effects models, depending on the magnitude of heterogeneity. A total of 38 studies (917 patients) were included. The overall survival rate for critically ill obstetric patients supported by ECMO was 65% (56-74%). Among these, the survival rates for antepartum and postpartum patients were 70% (55-84%) and 63% (47-78%) respectively. The survival rates of obstetric patients supported by VV-ECMO and VA-ECMO were 70% (56-83%) and 56% (44-68%), respectively. This article systematically reports the survival rate of critically ill obstetric patients under ECMO support. The survival rate for these patients is significantly higher than the overall survival rate of all patients receiving ECMO support. Survival rates were similar for prenatal and postpartum patients but survival rates for patients supported by VV-ECMO were significantly higher than those supported by VA-ECMO. Further research is needed to explore the benefits of ECMO for obstetric patients with different disease types.

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产科病人的体外膜肺氧合：一项荟萃分析。

危重急症患者和产科病人是死亡率很高的特殊临床人群。体外膜肺氧合（ECMO）逐渐被用于产科急危重症患者，并显示出巨大优势。我们系统地检索了 PubMed、Embase、Web of Science、中国 CNKI 数据库和 Cochrane 图书馆数据库，检索时间从最早的可用日期到 2024 年 3 月 15 日，以获得关于产科患者体外膜氧合的相关研究。筛选文献后，根据异质性的大小，采用随机效应或固定效应模型对数据进行独立提取和汇总。共纳入 38 项研究（917 名患者）。在 ECMO 支持下，危重产科病人的总存活率为 65%（56-74%）。其中，产前和产后患者的存活率分别为 70% (55-84%) 和 63% (47-78%)。在 VV-ECMO 和 VA-ECMO 支持下，产科病人的存活率分别为 70% (56-83%) 和 56% (44-68%)。本文系统地报告了接受 ECMO 支持的危重产科病人的存活率。这些患者的存活率明显高于接受 ECMO 支持的所有患者的总体存活率。产前和产后患者的存活率相似，但接受 VV-ECMO 支持的患者的存活率明显高于接受 VA-ECMO 支持的患者。需要进一步研究探讨 ECMO 对不同疾病类型的产科患者的益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.