Microfluidics for foodborne bacteria analysis: Moving toward multiple technologies integration.

Abstract

Food security related to bacterial pathogens has seriously threatened human life and caused public health problems. Most of the reported methods are targeted at known major pathogens commonly found in food samples, but to some extent, they have the disadvantage of lacking simplicity, speed, high throughput, and high sensitivity. Microfluidics has become a promising tool for foodborne bacteria analysis and addresses the above limitations. In this perspective, we briefly discussed the ongoing research and development in this field. We outline the major types of microfluidics, the strategies of target biorecognition, and signal amplification technologies in the microfluidic system for the foodborne bacteria analysis. We also proposed the future directions of microfluidics for foodborne bacterial analysis, which aims to integrate multiple technologies toward intelligent analysis with high selectivity and sensitivity for unknown samples, multiple bacterial detection, and simultaneous detection of multiple food pollutants.