Decoy cells detected in the urine of a patient with complex karyotype Myelodysplastic neoplasms who underwent umbilical cord blood transplantation: a case report.

IF 2.2 4区医学 Q2 UROLOGY & NEPHROLOGY

BMC Nephrology Pub Date : 2024-11-05 DOI:10.1186/s12882-024-03838-x

Yuli Zhou, Siqi Zhu, Huanli Fang, Fuxian Zhou, Juan Jin

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Abstract

Background: Currently, few literature reports document cases of decoy cells in the urine of umbilical cord blood transplant patients. The majority of the literature indicates that decoy cells are frequently identified in the urine of kidney transplant recipients.

Case presentation: This case report describes a patient with Myelodysplastic Neoplasms featuring a complex karyotype who underwent umbilical cord blood transplantation. Postoperative urinary cytology revealed decoy cells, and subsequent BK virus nucleic acid testing was positive. However, the routine use of antiviral drugs by the physicians led to insufficient attention to the decoy cells and BK virus, culminating in hemorrhagic cystitis.

Conclusions: Urine cytology is a simple, intuitive, rapid, and cost-effective analytical method. The presence of decoy cells in the urine can serve as an indicator for infection screening and provide a clue for clinical doctors: Detection of decoy cells in urine should prompt a more vigorous antiviral response to mitigate the risk of complications like hemorrhagic cystitis.

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在一名接受脐带血移植的复杂核型骨髓增生异常肿瘤患者的尿液中检测到诱饵细胞：病例报告。

背景：目前，有关脐带血移植患者尿液中出现诱饵细胞的文献报道很少。大多数文献表明，肾移植受者的尿液中经常发现诱饵细胞：本病例报告描述的是一名骨髓增生异常肿瘤患者，其核型复杂，接受了脐带血移植手术。术后尿液细胞学检查发现诱饵细胞，随后进行的 BK 病毒核酸检测呈阳性。然而，医生常规使用抗病毒药物，导致对诱饵细胞和BK病毒重视不够，最终导致出血性膀胱炎：尿液细胞学是一种简单、直观、快速且经济有效的分析方法。结论：尿液细胞学是一种简单、直观、快速、经济的分析方法，尿液中出现的诱饵细胞可作为感染筛查的指标，并为临床医生提供线索：在尿液中检测到诱饵细胞应促使采取更有力的抗病毒措施，以降低出血性膀胱炎等并发症的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Nephrology UROLOGY & NEPHROLOGY-

CiteScore

4.30

自引率

0.00%

发文量

375

审稿时长

3-8 weeks

期刊介绍： BMC Nephrology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of kidney and associated disorders, as well as related molecular genetics, pathophysiology, and epidemiology.