Yuxiang Zhu, Shenghan Guo, Dharneedar Ravichandran, Arunachalam Ramanathan, M Taylor Sobczak, Alaina F Sacco, Dhanush Patil, Sri Vaishnavi Thummalapalli, Tiffany V Pulido, Jessica N Lancaster, Johnny Yi, Jeffrey L Cornella, David G Lott, Xiangfan Chen, Xuan Mei, Yu Shrike Zhang, Linbing Wang, Xianqiao Wang, Yiping Zhao, Mohammad K Hassan, Lindsay B Chambers, Taylor G Theobald, Sui Yang, Liang Liang, Kenan Song
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引用次数: 0
Abstract
3D printing, also known as additive manufacturing, holds immense potential for rapid prototyping and customized production of functional health-related devices. With advancements in polymer chemistry and biomedical engineering, polymeric biomaterials have become integral to 3D-printed biomedical applications. However, there still exists a bottleneck in the compatibility of polymeric biomaterials with different 3D printing methods, as well as intrinsic challenges such as limited printing resolution and rates. Therefore, this review aims to introduce the current state-of-the-art in 3D-printed functional polymeric health-related devices. It begins with an overview of the landscape of 3D printing techniques, followed by an examination of commonly used polymeric biomaterials. Subsequently, examples of 3D-printed biomedical devices are provided and classified into categories such as biosensors, bioactuators, soft robotics, energy storage systems, self-powered devices, and data science in bioplotting. The emphasis is on exploring the current capabilities of 3D printing in manufacturing polymeric biomaterials into desired geometries that facilitate device functionality and studying the reasons for material choice. Finally, an outlook with challenges and possible improvements in the near future is presented, projecting the contribution of general 3D printing and polymeric biomaterials in the field of healthcare.
三维打印又称增材制造,在快速原型设计和定制生产与健康相关的功能性设备方面具有巨大的潜力。随着聚合物化学和生物医学工程的发展,聚合物生物材料已成为三维打印生物医学应用不可或缺的一部分。然而,高分子生物材料与不同三维打印方法的兼容性仍存在瓶颈,同时还存在打印分辨率和速度有限等内在挑战。因此,本综述旨在介绍当前 3D 打印功能性聚合物健康相关设备的最新进展。文章首先概述了三维打印技术的现状,然后对常用的聚合物生物材料进行了研究。随后,提供了 3D 打印生物医学设备的实例,并将其分为生物传感器、生物致动器、软机器人、储能系统、自供电设备和生物绘图中的数据科学等类别。重点是探索三维打印技术在将聚合物生物材料制造成所需几何形状以促进设备功能方面的现有能力,并研究选择材料的原因。最后,展望了不久的将来所面临的挑战和可能的改进,预测了普通三维打印和聚合物生物材料在医疗保健领域的贡献。
期刊介绍:
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.