Blazing Carbon Dots: Unfolding its Luminescence Mechanism to Photoinduced Biomedical Applications.

IF 3.5 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2024-11-05 DOI:10.1002/asia.202401098

Nirmiti Mate, Vinita Satwani, Pranav Kumar, Shaikh M Mobin

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引用次数: 0

Abstract

Carbon dots (CDs) are carbon-based nanomaterials that have garnered immense interest due to their exceptional photophysical and optoelectronic properties. They have been employed extensively for biomedical imaging and phototherapy due to their superb water dispersibility, low toxicity, outstanding biocompatibility, and exceptional tissue permeability. This review summarizes the luminescence mechanism of CDs. The modification in CDs via various doping routes is comprehensively reviewed, and the effect of such alterations on their photophysical properties, such as photoluminescence (PL), absorbance, and reactive oxygen species generation ability, is also highlighted. This review also aims to summarize the role of CDs in cellular imaging and fluorescence lifetime imaging for cellular metabolism. Subsequently, recent advancements and the future prospects of CDs as nanotheranostic agents have been discussed. Herein, we have discussed the role of CDs in photothermal, photodynamic, and synergistic therapy of anticancer, antiviral, and antibacterial applications. The overall summary of the review highlights the future prospects of CD-based research in bioimaging and biomedicine.

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炽热碳点：揭示其发光机制，实现光诱导生物医学应用。

碳点（CD）是一种碳基纳米材料，因其卓越的光物理和光电特性而备受关注。由于其极佳的水分散性、低毒性、出色的生物相容性和优异的组织渗透性，它们已被广泛用于生物医学成像和光疗。本综述总结了光盘的发光机理。全面综述了通过各种掺杂途径对光盘进行改性的情况，并重点介绍了这些改性对其光物理性质（如光致发光（PL）、吸光度和活性氧生成能力）的影响。本综述还旨在总结 CD 在细胞成像和细胞代谢荧光寿命成像中的作用。随后，还讨论了作为纳米otheranostic 剂的 CD 的最新进展和未来前景。在此，我们讨论了光盘在光热、光动力以及抗癌、抗病毒和抗菌应用的协同治疗中的作用。综述强调了基于光盘的生物成像和生物医学研究的未来前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).