Visible-light-promoted aerobic synthesis of phenanthridinones from biaryl-2-oxamic acids

IF 4.1 3区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Photochemistry and Photobiology A-chemistry Pub Date : 2024-10-24 DOI:10.1016/j.jphotochem.2024.116113

引用次数: 0

Abstract

Phenanthridinones is an important structure found in natural products and biologically active molecules. An intramolecular decarboxylative cyclization of biaryl-2-oxamic acids is here presented to generate phenanthridinones, utilizing organic dye (4CzIPN) as the photocatalyst and base (K₃PO₄) in air at room temperature. The protocol exhibits great functional group tolerance, good to excellent yields, and scaled up application.

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双芳基-2-氧肟酸在可见光促进下有氧合成菲啶酮类化合物

菲啶酮是天然产物和生物活性分子中的一种重要结构。本文介绍了利用有机染料（4CzIPN）作为光催化剂和碱（K3PO4）在室温空气中对双芳基-2-氧肟酸进行分子内脱羧环化生成菲啶酮的方法。该方法对官能团有很好的耐受性，产率高至极佳，并可扩大应用范围。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Photochemistry and Photobiology A-chemistry 化学-物理化学

CiteScore

7.90

自引率

7.00%

发文量

580

审稿时长

48 days

期刊介绍： JPPA publishes the results of fundamental studies on all aspects of chemical phenomena induced by interactions between light and molecules/matter of all kinds. All systems capable of being described at the molecular or integrated multimolecular level are appropriate for the journal. This includes all molecular chemical species as well as biomolecular, supramolecular, polymer and other macromolecular systems, as well as solid state photochemistry. In addition, the journal publishes studies of semiconductor and other photoactive organic and inorganic materials, photocatalysis (organic, inorganic, supramolecular and superconductor). The scope includes condensed and gas phase photochemistry, as well as synchrotron radiation chemistry. A broad range of processes and techniques in photochemistry are covered such as light induced energy, electron and proton transfer; nonlinear photochemical behavior; mechanistic investigation of photochemical reactions and identification of the products of photochemical reactions; quantum yield determinations and measurements of rate constants for primary and secondary photochemical processes; steady-state and time-resolved emission, ultrafast spectroscopic methods, single molecule spectroscopy, time resolved X-ray diffraction, luminescence microscopy, and scattering spectroscopy applied to photochemistry. Papers in emerging and applied areas such as luminescent sensors, electroluminescence, solar energy conversion, atmospheric photochemistry, environmental remediation, and related photocatalytic chemistry are also welcome.