Intramedullary nail fixation versus open reduction and internal fixation for treatment of adult diaphyseal forearm fractures: a systematic review and meta-analysis.

IF 2.8 3区 医学 Q1 ORTHOPEDICS
McKenna W Box, Samuel D Stegelmann, Grayson A Domingue, Monica E Wells, Neil J Werthmann, Cornelis J Potgieter, John T Riehl
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引用次数: 0

Abstract

Background: Diaphyseal radius and ulna fractures require surgical fixation in adults. Open reduction and internal fixation (ORIF) have been considered the gold standard of treatment. The recent development of an interlocking intramedullary nail (IMN) has provided an alternative treatment method for these fractures. The objective of this meta-analysis is to compare the outcomes and complications of IMN versus ORIF for diaphyseal forearm fractures in adults.

Methods: MEDLINE and Embase were searched from January 1, 2000, through January 7, 2024. All English-language studies were included comparing radiographic and functional outcomes for interlocking IMN fixation and ORIF of diaphyseal forearm fractures in adults (age ≥ 18 years). Study demographics, fracture data, functional outcomes, radiographic outcomes, and complications were extracted. Study quality was determined using the ROBINS-I criteria for cohort studies and the Cochrane risk of bias 2.0 (RoB 2) tool for randomized controlled trials. Meta-analysis of included studies used odds ratios and standardized mean difference when appropriate. Data was analyzed using subgroups of all diaphyseal fractures (including isolated radius or ulna fractures) and those with BBFFs.

Results: Nine studies were included for analysis. There were 42 isolated radius, 80 isolated ulna, and 116 both-bone fractures (BBFF) treated with IMN and 36 radius, 81 ulna, and 116 both-bone fractures treated with ORIF. Compared to ORIF, IMN of diaphyseal forearm fractures appeared to be associated with shorter operative times and a lower overall complication rate. Time-to-union and the rate of nonunion following IMN were similar to ORIF. According to the Grace-Eversmann score, functional outcomes tended to be better following IMN, but DASH scores were similar between fixation strategies.

Conclusions: Our findings suggest that interlocking IMN can be a safe and effective treatment option for simple and complex diaphyseal forearm fractures in adults. Further high-quality studies are needed to define indications for treating diaphyseal fractures with an interlocking IMN.

Level of evidence: Therapeutic Level IV.

髓内钉固定与切开复位内固定治疗成人前臂骨骺骨折:系统综述与荟萃分析。
背景:成人桡骨和尺骨骨骺骨折需要手术固定。切开复位内固定术(ORIF)一直被认为是治疗的黄金标准。最近开发的交锁髓内钉(IMN)为这些骨折提供了另一种治疗方法。本荟萃分析的目的是比较IMN与ORIF治疗成人前臂骨骺骨折的疗效和并发症:方法:检索了 2000 年 1 月 1 日至 2024 年 1 月 7 日期间的 MEDLINE 和 Embase。方法:检索了 2000 年 1 月 1 日至 2024 年 1 月 7 日期间的 MEDLINE 和 Embase,纳入了所有比较成人(年龄≥18 岁)前臂骺骨折交锁 IMN 固定和 ORIF 的影像学和功能性结果的英语研究。提取了研究的人口统计学、骨折数据、功能性结果、放射学结果和并发症。对队列研究采用 ROBINS-I 标准,对随机对照试验采用 Cochrane 偏倚风险 2.0 (RoB 2) 工具确定研究质量。对纳入研究的 Meta 分析酌情使用了几率比和标准化平均差。数据分析采用了所有骺端骨折(包括孤立的桡骨或尺骨骨折)和BBFFs骨折的亚组:结果:共纳入九项研究进行分析。其中42例孤立桡骨骨折、80例孤立尺骨骨折和116例双骨骨折(BBFF)接受了IMN治疗,36例桡骨骨折、81例尺骨骨折和116例双骨骨折接受了ORIF治疗。与 ORIF 相比,IMN 治疗前臂骨骺骨折的手术时间更短,总体并发症发生率更低。IMN术后的愈合时间和不愈合率与ORIF相似。根据Grace-Eversmann评分,IMN术后的功能预后往往更好,但不同固定策略的DASH评分相似:我们的研究结果表明,联锁IMN是治疗成人简单和复杂前臂骨骺骨折的一种安全有效的方法。需要进一步开展高质量的研究,以确定使用联锁IMN治疗骺端骨折的适应症:证据等级:治疗四级。
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来源期刊
CiteScore
4.10
自引率
7.70%
发文量
494
审稿时长
>12 weeks
期刊介绍: Journal of Orthopaedic Surgery and Research is an open access journal that encompasses all aspects of clinical and basic research studies related to musculoskeletal issues. Orthopaedic research is conducted at clinical and basic science levels. With the advancement of new technologies and the increasing expectation and demand from doctors and patients, we are witnessing an enormous growth in clinical orthopaedic research, particularly in the fields of traumatology, spinal surgery, joint replacement, sports medicine, musculoskeletal tumour management, hand microsurgery, foot and ankle surgery, paediatric orthopaedic, and orthopaedic rehabilitation. The involvement of basic science ranges from molecular, cellular, structural and functional perspectives to tissue engineering, gait analysis, automation and robotic surgery. Implant and biomaterial designs are new disciplines that complement clinical applications. JOSR encourages the publication of multidisciplinary research with collaboration amongst clinicians and scientists from different disciplines, which will be the trend in the coming decades.
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