Electrochemically simple, sensitive, and clean method for monitoring norfloxacin in advanced oxidative processes

IF 4.1 3区化学 Q1 CHEMISTRY, ANALYTICAL

Journal of Electroanalytical Chemistry Pub Date : 2024-10-28 DOI:10.1016/j.jelechem.2024.118752

Crislânia Carla de Oliveira Morais , Keurison Figueredo Magalhães , Elisama Vieira dos Santos , Suely Souza Leal Castro , Carlos A. Martínez-Huitle

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引用次数: 0

Abstract

In this work, an amperometric analysis strategy using a carbon fiber (CF) rod as an anode was developed to follow the degradation process of the norfloxacin (NOR) molecule via electrochemical advanced oxidation processes (EAOP). The voltammetric study showed that drug oxidation is an irreversible process which involves, in the determining stage of the reaction, a proton and an electron in an EC (electron transfer followed by chemical reaction) mechanism. After optimizing the electroanalytical conditions, CF sensor showed a linear amperometric response at concentrations ranging from 1.6 μmol L⁻¹ to 30.0 μmol L⁻¹, with detection and quantification limits of 0.5 μmol L⁻¹ and 1.8 μmol L⁻¹, respectively, which are sufficient to enable in monitoring the drug during its electrolytic degradation. The results clearly showed that the by-products generated during drug degradation do not interfere with the current signal. Other application scenarios were evaluated, such as the determination of NOR in river waters and in the presence of different drug degradation by-products, obtained after EAOPs in chloride-containing medium, and no interference was observed during the electroanalysis. Therefore, the proposed analytical methodology is promising for monitoring and controlling the treatment of water contaminated with NOR antibiotic.

查看原文本刊更多论文

在高级氧化过程中监测诺氟沙星的简单、灵敏和清洁的电化学方法

在这项工作中，开发了一种使用碳纤维（CF）棒作为阳极的安培分析策略，通过电化学高级氧化过程（EAOP）跟踪诺氟沙星（NOR）分子的降解过程。伏安法研究表明，药物氧化是一个不可逆的过程，在反应的决定阶段，质子和电子参与了 EC（电子转移后的化学反应）机制。优化电分析条件后，CF 传感器在 1.6 μmol L-1 至 30.0 μmol L-1 的浓度范围内显示出线性安培响应，检出限和定量限分别为 0.5 μmol L-1 和 1.8 μmol L-1，足以监测药物的电解降解过程。结果清楚地表明，药物降解过程中产生的副产物不会干扰电流信号。还对其他应用场景进行了评估，例如测定河水中的 NOR，以及在含氯介质中进行 EAOPs 后获得的不同药物降解副产物的情况，在电分析过程中未观察到干扰。因此，所提出的分析方法有望用于监测和控制 NOR 抗生素污染水的处理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Electroanalytical Chemistry 化学-电化学

CiteScore

7.80

自引率

6.70%

发文量

912

审稿时长

2.4 months

期刊介绍： The Journal of Electroanalytical Chemistry is the foremost international journal devoted to the interdisciplinary subject of electrochemistry in all its aspects, theoretical as well as applied. Electrochemistry is a wide ranging area that is in a state of continuous evolution. Rather than compiling a long list of topics covered by the Journal, the editors would like to draw particular attention to the key issues of novelty, topicality and quality. Papers should present new and interesting electrochemical science in a way that is accessible to the reader. The presentation and discussion should be at a level that is consistent with the international status of the Journal. Reports describing the application of well-established techniques to problems that are essentially technical will not be accepted. Similarly, papers that report observations but fail to provide adequate interpretation will be rejected by the Editors. Papers dealing with technical electrochemistry should be submitted to other specialist journals unless the authors can show that their work provides substantially new insights into electrochemical processes.