Functionality loss due to COVID-19 hospitalisation in older adults recovers with inpatient rehabilitation: A systematic review and meta-analysis

IF 3.9

Experimental gerontology Pub Date : 2024-11-05 DOI:10.1016/j.exger.2024.112617

Henrique Monteiro Lapo , Amanda Veiga Sardeli , Lilian Oliveira Mariano , Fiona Jayne Howroyd , Paulo Roberto Sokoll , Elizabeth Sapey , Mara Patrícia Traina Chacon-Mikahil

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引用次数: 0

Abstract

Introduction

Older adults are more likely to acquire the severe manifestation of COVID-19 and the hospitalised survivors experience significant functionality loss. Thus, we aimed to identify the level of functionality in older adults hospitalised due to COVID-19, and the effect of inpatient rehabilitation upon functional recovery.

Methods

A search was performed on July 2024, across five databases to retrieve studies assessing functionality in patients during COVID-19 hospitalisation, with or without rehabilitation.

Results

At admission, higher functionality was significantly higher for survivors than non survivors (standardized mean difference (SMD): 0.83 [0.56; 1.09]). The effect of inpatient rehabilitation on functionality was tested among 38 arms across studies. Inpatient rehabilitation improved functionality SMD across all indexes (1.47 [1.18; 1.77], P ≤ 0.001), with greatest effect in the patients >70 years (2.84 [1.74, 3.93], P = 0.006), compared to their counterparts.

Conclusion

Hospitalisation due to COVID-19 reduced functionality to a higher extent in older adults above 70 years. Inpatient rehabilitation was effective to improve functionality in both age groups.

Protocol registration

PROSPERO CRD42021278619.

Abstract Image

查看原文本刊更多论文

老年人因 COVID-19 住院而丧失的功能可通过住院康复恢复：系统回顾和荟萃分析。

简介老年人更容易患上表现严重的 COVID-19，而住院幸存者的功能会明显减退。因此，我们旨在确定因 COVID-19 而住院的老年人的功能水平，以及住院康复对功能恢复的影响：方法：我们于 2024 年 7 月在五个数据库中进行了检索，以检索评估 COVID-19 住院期间患者功能的研究，无论是否进行了康复治疗：入院时，幸存者的功能显著高于非幸存者（标准化平均差异（SMD）：0.83 [0.56; 1.09]）。住院康复治疗对功能的影响在38项研究中进行了测试。与同类患者相比，住院康复治疗改善了所有指标的功能性SMD（1.47 [1.18; 1.77]，P ≤ 0.001），对70岁以上患者的影响最大（2.84 [1.74, 3.93]，P = 0.006）：结论：COVID-19导致的住院治疗对70岁以上老年人的功能影响更大。住院康复治疗可有效改善这两个年龄组的功能：PREMCORD42021278619。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Experimental gerontology Ageing, Biochemistry, Geriatrics and Gerontology

CiteScore

6.70

自引率

0.00%

发文量

审稿时长

66 days