Prevalence of Congenital Anomalies in Iran.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Archives of Iranian Medicine Pub Date : 2024-10-01 DOI:10.34172/aim.31287

Ahmad Khaleghnejad-Tabari, Saeed Dastgiri, Hamid Soori, Alireza Ansari-Moghaddam, Haleh Ghaem, Mahmoud Latifi, Mohammad Reza Maracy, Saeed Aslanabadi, Fathollah Roshanzamir, Hamid Reza Forootan, Mehran Peivaste, Mehrdad Hoseinpour, Nasibeh Khaleghnejad-Tabari, Arameh Abbasian, Arghavan Haj-Sheykholeslami

{"title":"Prevalence of Congenital Anomalies in Iran.","authors":"Ahmad Khaleghnejad-Tabari, Saeed Dastgiri, Hamid Soori, Alireza Ansari-Moghaddam, Haleh Ghaem, Mahmoud Latifi, Mohammad Reza Maracy, Saeed Aslanabadi, Fathollah Roshanzamir, Hamid Reza Forootan, Mehran Peivaste, Mehrdad Hoseinpour, Nasibeh Khaleghnejad-Tabari, Arameh Abbasian, Arghavan Haj-Sheykholeslami","doi":"10.34172/aim.31287","DOIUrl":null,"url":null,"abstract":"Background: Annually, 3-8 million infants are born with congenital anomalies worldwide, ranging from 3% to 7% of births in different countries. This study aimed to investigate the nationwide epidemiological features of birth defects in Iran.Methods: This cross-sectional study was conducted in six major regions across Iran. The data sources were the maternity facilities affiliated with regional universities of medical sciences. All children were examined by obstetricians, pediatricians, or midwives at birth, and newborns were followed until discharge from the facility for health status, maturity, and congenital defects.Results: A total of 138,643 births were registered in the maternity facilities across the study regions. Among these newborns, 3,458 cases were diagnosed with congenital anomalies, representing an overall prevalence rate of 249.4 per 10000 births (95% CI: 241.2-257.8). Genital organ anomalies exhibited the highest rates of defects in the country with 92.7 per 10000 births (95% CI: 86.4-98.9), followed by limb anomalies at 83.3 per 10000 births (95% CI: 77.4-89.3). The prevalence of respiratory system, chromosomal, and urinary tract anomalies was less than 10 per 10000 births.Conclusion: Until a national registry for congenital anomalies is established, this study provides essential data on the magnitude of the health problems caused by congenital anomalies in Iran. The findings would be vital for planning and evaluating antenatal screening for birth defects, particularly for high-risk groups and regions in the country.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 10","pages":"545-550"},"PeriodicalIF":1.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532651/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Iranian Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.34172/aim.31287","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Annually, 3-8 million infants are born with congenital anomalies worldwide, ranging from 3% to 7% of births in different countries. This study aimed to investigate the nationwide epidemiological features of birth defects in Iran.

Methods: This cross-sectional study was conducted in six major regions across Iran. The data sources were the maternity facilities affiliated with regional universities of medical sciences. All children were examined by obstetricians, pediatricians, or midwives at birth, and newborns were followed until discharge from the facility for health status, maturity, and congenital defects.

Results: A total of 138,643 births were registered in the maternity facilities across the study regions. Among these newborns, 3,458 cases were diagnosed with congenital anomalies, representing an overall prevalence rate of 249.4 per 10000 births (95% CI: 241.2-257.8). Genital organ anomalies exhibited the highest rates of defects in the country with 92.7 per 10000 births (95% CI: 86.4-98.9), followed by limb anomalies at 83.3 per 10000 births (95% CI: 77.4-89.3). The prevalence of respiratory system, chromosomal, and urinary tract anomalies was less than 10 per 10000 births.

Conclusion: Until a national registry for congenital anomalies is established, this study provides essential data on the magnitude of the health problems caused by congenital anomalies in Iran. The findings would be vital for planning and evaluating antenatal screening for birth defects, particularly for high-risk groups and regions in the country.

查看原文本刊更多论文

伊朗先天性畸形的发病率。

背景：全世界每年有 300-800 万名婴儿出生时患有先天性畸形，占不同国家新生儿的 3%-7% 不等。本研究旨在调查伊朗全国范围内出生缺陷的流行病学特征：这项横断面研究在伊朗的六个主要地区进行。数据来源是地区医科大学附属的产科机构。所有儿童在出生时均由产科医生、儿科医生或助产士进行检查，并对新生儿的健康状况、成熟度和先天性缺陷进行跟踪，直至其出院：研究地区的产科机构共登记了 138 643 例新生儿。在这些新生儿中，有 3,458 例被诊断出患有先天性畸形，总患病率为每 10000 例新生儿中有 249.4 例（95% CI：241.2-257.8）。生殖器官畸形的发病率在全国最高，每 10000 名新生儿中有 92.7 例（95% CI：86.4-98.9），其次是肢体畸形，每 10000 名新生儿中有 83.3 例（95% CI：77.4-89.3）。呼吸系统畸形、染色体畸形和泌尿系统畸形的发病率低于每万名新生儿 10 例：在建立全国先天性畸形登记册之前，这项研究提供了有关伊朗先天性畸形造成的健康问题严重程度的重要数据。研究结果对规划和评估出生缺陷产前筛查至关重要，尤其是对伊朗的高危人群和地区。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Archives of Iranian Medicine 医学-医学：内科

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

3-8 weeks

期刊介绍： Aim and Scope: The Archives of Iranian Medicine (AIM) is a monthly peer-reviewed multidisciplinary medical publication. The journal welcomes contributions particularly relevant to the Middle-East region and publishes biomedical experiences and clinical investigations on prevalent diseases in the region as well as analyses of factors that may modulate the incidence, course, and management of diseases and pertinent medical problems. Manuscripts with didactic orientation and subjects exclusively of local interest will not be considered for publication.The 2016 Impact Factor of "Archives of Iranian Medicine" is 1.20.