Development and Preliminary Psychometric Testing of a Brief Tool to Measure Medication Adherence in Older Populations.

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

Clinical Interventions in Aging Pub Date : 2024-10-30 eCollection Date: 2024-01-01 DOI:10.2147/CIA.S480480

Paolo Iovino, Paola Obbia, Vincenzo De Luca, Clara Donnoli, Lola Patumi, Lisa Leonardini, Ernesto Palummeri, Manuela Ruatta, Anna Maddalena Basso, Yari Longobucco, Laura Rasero, Giuseppe Liotta, Maddalena Illario

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引用次数: 0

Abstract

Purpose: Chronic diseases in older age are major sources of burden for healthcare systems. Compliance with medications is the key to treatment success for these patients, especially for frail individuals living in community settings. However, adherence to long-term medications in this population is not optimal, which leads to the need for frequent screening of compliance within large-scale public health surveys. In this context, a brief, simple and valid measure capturing medication adherence is not yet available. This study aims to develop and psychometrically test the Therapeutic Adherence Scale, a brief four-item tool that measures medication adherence in community-dwelling older adults affected by chronic diseases.

Methods: We conducted a three-phase process of instrument development, content validity assessment and psychometric testing.

Results: Of the candidate nine items derived from a review of the literature, only four were deemed essential to capture intentional and nonintentional nonadherence. These items underwent structural validity, convergent and known-groups validity, and internal consistency on a sample of 269 participants (mean age = 7.91 years, SD = 7.26). Confirmatory factor analysis confirmed satisfactory fit indices (RMSEA = 0.000, CFI = 1.00, TLI = 1.00). Scores of the TAS were higher for those perceiving loneliness (ρ = 0.33, p < 0.001), those declaring memory loss in the last year (ρ = 0.29, p < 0.001), and those exhibiting worse mental quality of life (ρ = -0.15, p = 0.03) compared with the other groups. Cronbach's alpha and split-half reliability coefficients were acceptable, with values of 0.68 and 0.77, respectively.

Conclusion: The Therapeutic Adherence Scale is a brief, valid and reliable self-report measure of medication adherence that can be used in practice and research to screen patients living in community settings. This tool is also free to use, which contributes to advancing knowledge on the field of medication adherence of older adults affected by chronic diseases.

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开发并初步测试测量老年人用药依从性的简易工具

目的：老年慢性病是医疗保健系统的主要负担来源。对药物的依从性是这些患者治疗成功的关键，尤其是对生活在社区环境中的体弱者而言。然而，这类人群长期服药的依从性并不理想，因此需要在大规模的公共卫生调查中对其依从性进行频繁筛查。在这种情况下，目前还没有一种简明、简单而有效的方法来衡量服药依从性。本研究旨在开发治疗依从性量表并对其进行心理测试，该量表是一种简短的四项目工具，用于测量社区中受慢性病影响的老年人的用药依从性：我们分三个阶段进行了工具开发、内容效度评估和心理测试：结果：在查阅文献后得出的 9 个候选项目中，只有 4 个项目被认为对捕捉有意和无意的不依从性至关重要。这些项目在269名参与者（平均年龄=7.91岁，标准差=7.26）的样本中进行了结构效度、收敛效度和已知群体效度以及内部一致性测试。确认性因素分析证实拟合指数令人满意（RMSEA = 0.000，CFI = 1.00，TLI = 1.00）。与其他组别相比，孤独感（ρ = 0.33，p < 0.001）、去年记忆力减退（ρ = 0.29，p < 0.001）和精神生活质量较差（ρ = -0.15，p = 0.03）者的 TAS 分数较高。Cronbach'sα和分半信度系数均可接受，分别为0.68和0.77：治疗依从性量表是一种简短、有效和可靠的自我报告式药物治疗依从性测量方法，可用于实践和研究中，对生活在社区环境中的患者进行筛查。该工具还可以免费使用，有助于增进对受慢性病影响的老年人用药依从性的了解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Interventions in Aging GERIATRICS & GERONTOLOGY-

CiteScore

6.80

自引率

2.80%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Clinical Interventions in Aging, is an online, peer reviewed, open access journal focusing on concise rapid reporting of original research and reviews in aging. Special attention will be given to papers reporting on actual or potential clinical applications leading to improved prevention or treatment of disease or a greater understanding of pathological processes that result from maladaptive changes in the body associated with aging. This journal is directed at a wide array of scientists, engineers, pharmacists, pharmacologists and clinical specialists wishing to maintain an up to date knowledge of this exciting and emerging field.