{"title":"Meta-analysis of the efficacy of the erector spinae plane block after spinal fusion surgery.","authors":"Yi He, Heng Liu, Peng Ma, Jing Zhang, Qiulian He","doi":"10.7717/peerj.18332","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the efficacy of erector spinal plane block (ESPB) after spinal fusion surgery in this study.</p><p><strong>Methods: </strong>The PubMed, Embase, Cochrane library, and Web of Science databases were searched with a search deadline of March 30, 2024, and Stata 15.0 was used to analyze the data from the included studies.</p><p><strong>Result: </strong>Nine randomized controlled trials involving 663 patients were included. Meta-analysis showed that EPSB could reduce pain scores at 2h (standard mean difference (SMD) = -0.78, 95% CI [-1.38 to -0.19], GRADE: Moderate), 6 h (SMD = -0.81, 95% CI [-1.23 to -0.38], GRADE: Moderate), 12 h (SMD = -0.59, 95% CI [-1.05 to -0.13], GRADE: Moderate), 24 h (SMD = -0.54, 95% CI [-0.86 to -0.21], GRADE: Moderate), 48 h (SMD = -0.40, 95% CI [-0.75 to -0.05], GRADE: Moderate) after spinal fusion surgery, as well as the PCA (analgesia medication use) (SMD = -1.67, 95% CI [-2.67 to -0.67], GRADE: Moderate). However, EPSB had no effect on intraoperative blood loss (SMD = -0.28, 95% CI [-1.03 to 0.47], GRADE: Low) and length of hospital stay (SMD = -0.27, 95% CI [-0.60-0.06], GRADE: Low).</p><p><strong>Conclusion: </strong>Combined with the current findings, EPSB may reduce pain scores in spinal fusion surgery, possibly reducing the use of postoperative analgesics. However, due to the limitations of the study, we need more high-quality, multi-center, large sample randomized controlled trials to merge.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531255/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"PeerJ","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.7717/peerj.18332","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To investigate the efficacy of erector spinal plane block (ESPB) after spinal fusion surgery in this study.
Methods: The PubMed, Embase, Cochrane library, and Web of Science databases were searched with a search deadline of March 30, 2024, and Stata 15.0 was used to analyze the data from the included studies.
Result: Nine randomized controlled trials involving 663 patients were included. Meta-analysis showed that EPSB could reduce pain scores at 2h (standard mean difference (SMD) = -0.78, 95% CI [-1.38 to -0.19], GRADE: Moderate), 6 h (SMD = -0.81, 95% CI [-1.23 to -0.38], GRADE: Moderate), 12 h (SMD = -0.59, 95% CI [-1.05 to -0.13], GRADE: Moderate), 24 h (SMD = -0.54, 95% CI [-0.86 to -0.21], GRADE: Moderate), 48 h (SMD = -0.40, 95% CI [-0.75 to -0.05], GRADE: Moderate) after spinal fusion surgery, as well as the PCA (analgesia medication use) (SMD = -1.67, 95% CI [-2.67 to -0.67], GRADE: Moderate). However, EPSB had no effect on intraoperative blood loss (SMD = -0.28, 95% CI [-1.03 to 0.47], GRADE: Low) and length of hospital stay (SMD = -0.27, 95% CI [-0.60-0.06], GRADE: Low).
Conclusion: Combined with the current findings, EPSB may reduce pain scores in spinal fusion surgery, possibly reducing the use of postoperative analgesics. However, due to the limitations of the study, we need more high-quality, multi-center, large sample randomized controlled trials to merge.
目的调查脊柱融合术后直立脊柱平面阻滞(ESPB)的疗效:方法:检索PubMed、Embase、Cochrane图书馆和Web of Science数据库,检索截止日期为2024年3月30日,并使用Stata 15.0分析纳入研究的数据:结果:共纳入9项随机对照试验,涉及663名患者。Meta分析表明,EPSB可降低2小时(标准平均差(SMD)=-0.78,95% CI [-1.38 to -0.19],GRADE:中度)、6小时(SMD=-0.81,95% CI [-1.23 to -0.38],GRADE:中度)、12小时(SMD=-0.59,95% CI [-1.05 to -0.13],GRADE:中度)、6小时(SMD=-0.81,95% CI [-1.23 to -0.38],GRADE:中度)、12小时(SMD=-0.59,95% CI [-1.05 to -0.13],GRADE:中度)的疼痛评分。13],GRADE:中度)、脊柱融合手术后 24 h(SMD = -0.54,95% CI [-0.86 to -0.21],GRADE:中度)、48 h(SMD = -0.40,95% CI [-0.75 to -0.05],GRADE:中度)以及 PCA(镇痛药物使用)(SMD =-1.67,95% CI [-2.67 to -0.67],GRADE:中度)。然而,EPSB对术中失血量(SMD = -0.28,95% CI [-1.03 to 0.47],GRADE:低)和住院时间(SMD = -0.27,95% CI [-0.60-0.06],GRADE:低)没有影响:结合目前的研究结果,EPSB 可降低脊柱融合手术中的疼痛评分,从而可能减少术后镇痛药的使用。然而,由于研究的局限性,我们需要更多高质量、多中心、大样本的随机对照试验来合并。
期刊介绍:
PeerJ is an open access peer-reviewed scientific journal covering research in the biological and medical sciences. At PeerJ, authors take out a lifetime publication plan (for as little as $99) which allows them to publish articles in the journal for free, forever. PeerJ has 5 Nobel Prize Winners on the Board; they have won several industry and media awards; and they are widely recognized as being one of the most interesting recent developments in academic publishing.