Measurement of cerebral venous oxygenation with quantitative susceptibility mapping after subarachnoid hemorrhage: A pilot study.

IF 2.6 Q2 CLINICAL NEUROLOGY
Journal of Central Nervous System Disease Pub Date : 2024-10-30 eCollection Date: 2024-01-01 DOI:10.1177/11795735241292185
Meng Qi, Lei Zhang, Ning Wang, Lidan Jiang, Hao Zhao, Wenjin Chen, Yueqiao Xu
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Abstract

Objective: We measured cerebral venous oxygenation after aneurysmal subarachnoid hemorrhage (aSAH) using quantitative susceptibility mapping (QSM) to explore its relationship with cognitive function.

Methods: Twenty participants, including 10 patients with aSAH and 10 healthy volunteers as the control group, were included. Patients with aSAH were evaluated at 2 days, 3 weeks, and 6 months after aSAH. Each participant underwent magnetic resonance imaging and completed the Montreal Cognitive Assessment (MoCA) at baseline, midpoint, and endpoint. QSM was used to determine the magnetic susceptibility of the cerebral veins. Furthermore, the relationship between MoCA and oxygen saturation in the cerebral veins was examined.

Results: The first scans of the cerebral veins and straight sinus susceptibility were considerably more significant in the aSAH group than in the healthy control group. At the 6-month follow-up, the mean oxygen saturation steadily increased in the aSAH group. Cerebral venous oxygen saturation was moderately correlated with MoCA (r = 0.5319, P = .0025).

Conclusion: QSM can be used to measure changes in cerebral venous oxygenation levels in patients with aSAH. During the acute phase of aSAH, there is a reduction in the oxygen saturation in the cerebral veins, and the shift in oxygen saturation levels may correlate with cognitive outcomes in patients with aSAH.

蛛网膜下腔出血后利用定量感度图测量脑静脉氧合:试点研究。
目的:我们使用定量易感性图谱(QSM)测量动脉瘤性蛛网膜下腔出血(aSAH)后的脑静脉氧合,以探讨其与认知功能的关系:方法:研究人员共 20 人,包括 10 名动脉瘤性蛛网膜下腔出血患者和 10 名作为对照组的健康志愿者。分别在脑梗死后 2 天、3 周和 6 个月对脑梗死患者进行评估。每位参与者都接受了磁共振成像检查,并在基线、中点和终点完成了蒙特利尔认知评估(MoCA)。QSM 用于确定脑静脉的磁感应强度。此外,还研究了 MoCA 与脑静脉血氧饱和度之间的关系:结果:与健康对照组相比,aSAH 组的首次脑静脉扫描和直窦磁感显著高于健康对照组。在 6 个月的随访中,aSAH 组的平均血氧饱和度稳步上升。脑静脉血氧饱和度与MoCA呈中度相关(r = 0.5319,P = .0025):结论:QSM 可用于测量 aSAH 患者脑静脉血氧饱和度的变化。结论:QSM 可用于测量 aSAH 患者脑静脉血氧饱和度的变化,在 aSAH 急性期,脑静脉血氧饱和度会降低,血氧饱和度的变化可能与 aSAH 患者的认知结果相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.90
自引率
0.00%
发文量
39
审稿时长
8 weeks
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