Time trends in incidence of pilonidal sinus disease from 1996 to 2021: A Danish population-based cohort study.

IF 2.9 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Colorectal Disease Pub Date : 2024-11-03 DOI:10.1111/codi.17227

Ida Kaad Faurschou, Rune Erichsen, Dietrich Doll, Susanne Haas

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引用次数: 0

Abstract

Aim: Pilonidal sinus disease (PSD) is a common condition, but no data on disease occurrence exist outside highly selected settings. The aim of this study was to assess time trends in the incidence of PSD in a nationwide setting.

Method: Using data from nationwide Danish registries, we identified 48 247 patients recorded with diagnostic or surgical procedure codes representing PSD between 1996 and 2021. We stratified by sex and computed the age-adjusted and age-specific incidence rate, comparing 5-year intervals with the incidence rate ratio (IRR).

Results: The overall incidence of PSD increased from 26.1 to 39.6/100 000 person-years (PY) from the period 1996-2000 to the period 2016-2021 (IRR 1.52, 95% CI 0.78-2.94). The incidence increased from 35.8 to 56.9/100 000 PY (IRR 1.59, 95% CI 0.52-4.89) in male patients and from 16.4 to 22.5/100 000 PY (IRR 1.37, 95% CI 0.68-2.76) in female patients. The peak of age-specific incidence was 215.7/100 000 PY (95% CI 206.1-245.4) among 20-year-old men and 107.9/100.000 PY (95% CI 100.0-114.0) among 18-year-old women. Over the study period, the median age at first hospital contact decreased from 27 years [interquartile range (IQR) 22-34 years) to 25 years (IQR 20-34 years) in men but remained stable around 23 years (IQR 18-32 years) in women. However, for both sexes, the highest increase in incidence was seen in early adolescence.

Conclusion: The incidence of PSD has increased significantly over the last decades. The increase is driven primarily by men and boys, with the highest increase in incidence seen in early adolescence. The increased burden of disease is not reflected in the literature, and more studies are warranted to understand the drivers of this development.

查看原文本刊更多论文

1996 年至 2021 年朝天鼻窦疾病发病率的时间趋势：一项基于丹麦人口的队列研究。

目的：蝶窦疾病（PSD）是一种常见病，但在高度选定的环境之外，却没有关于疾病发生率的数据。本研究旨在评估全国范围内 PSD 发病率的时间趋势：方法：我们利用丹麦全国登记处的数据，确定了 1996 年至 2021 年间 48 247 名记录有 PSD 诊断或手术代码的患者。我们按性别进行了分层，并计算了年龄调整后的发病率和年龄特异性发病率，比较了5年间隔的发病率比（IRR）：从1996-2000年到2016-2021年，PSD的总发病率从26.1/100 000人年增至39.6/100 000人年（IRR为1.52，95% CI为0.78-2.94）。男性患者的发病率从每 100 000 人年 35.8 例增加到 56.9 例（IRR 1.59，95% CI 0.52-4.89），女性患者的发病率从每 100 000 人年 16.4 例增加到 22.5 例（IRR 1.37，95% CI 0.68-2.76）。年龄特异性发病率的峰值是：20 岁男性为 215.7/100000PY（95% CI 206.1-245.4），18 岁女性为 107.9/100000PY（95% CI 100.0-114.0）。在研究期间，男性首次接触医院的中位年龄从 27 岁[四分位距（IQR）22-34 岁]降至 25 岁（IQR 20-34 岁），而女性则稳定在 23 岁（IQR 18-32）左右。然而，男女发病率的最高增长期都出现在青春期早期：结论：在过去几十年中，PSD 的发病率显著增加。结论：在过去的几十年中，PSD 的发病率大幅上升，主要是由男性和男童驱动的，而青春期早期的发病率增幅最高。文献中并未反映出疾病负担的增加，因此有必要开展更多研究，以了解这一发展的驱动因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Colorectal Disease 医学-胃肠肝病学

CiteScore

6.10

自引率

11.80%

发文量

406

审稿时长

1.5 months

期刊介绍： Diseases of the colon and rectum are common and offer a number of exciting challenges. Clinical, diagnostic and basic science research is expanding rapidly. There is increasing demand from purchasers of health care and patients for clinicians to keep abreast of the latest research and developments, and to translate these into routine practice. Technological advances in diagnosis, surgical technique, new pharmaceuticals, molecular genetics and other basic sciences have transformed many aspects of how these diseases are managed. Such progress will accelerate. Colorectal Disease offers a real benefit to subscribers and authors. It is first and foremost a vehicle for publishing original research relating to the demanding, rapidly expanding field of colorectal diseases. Essential for surgeons, pathologists, oncologists, gastroenterologists and health professionals caring for patients with a disease of the lower GI tract, Colorectal Disease furthers education and inter-professional development by including regular review articles and discussions of current controversies. Note that the journal does not usually accept paediatric surgical papers.