Risk factors for canine infectious respiratory disease complex and the pathogens associated with the disease.

IF 0.9 4区农林科学 Q3 VETERINARY SCIENCES

Canadian Veterinary Journal-revue Veterinaire Canadienne Pub Date : 2024-11-01

Zenhwa Ouyang, Daniel Joffe, J Scott Weese, Theresa Bernardo, Aimee Porter, Stephanie Villemaire, Marie-Eve Cardin, Ken Langelier, Jamie Mcgill-Worsley, Karren Prost, Zvonimir Poljak

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引用次数: 0

Abstract

Background: Canine infectious respiratory disease complex (CIRDC) is a common respiratory condition typically associated with high-density populations.

Objectives: The objectives of this study were to determine the most common pathogens involved in CIRDC and to identify risk factors (pathogens, environmental exposures) associated with the diagnosis.

Animals and procedure: A prospective, multi-clinic, case-control study was conducted in Canada from April 2017 to May 2018. A total of 110 dogs (74 cases, 36 controls) were enrolled by participating veterinary clinics. Pathogens were detected using a respiratory PCR panel.

Results: Canine parainfluenza virus (CPIV), Bordetella bronchiseptica, and canine respiratory coronavirus (CRCoV) were detected in cases only. According to 2 logistic regression models, detection of CPIV (OR: 14.42; 95% CI: 2.24 to ∞) and CRCoV (OR: 8.64; 95% CI: 1.26 to ∞) were associated with CIRDC disease status. In another model, exposures to multiple-dog gatherings also increased the odds (OR: 3.39; 95% CI: 1.26 to 9.81) of CIRDC diagnosis.

Conclusions: Consistent with other studies, this study determined that CPIV, CRCoV, and B. bronchiseptica were important contributors to CIRDC cases. Detection of CPIV and CRCoV and exposure to areas of dog gatherings were identified as having a role in disease status when evaluated statistically, under the conditions of this study.

本刊更多论文

犬呼吸道传染病复合病的风险因素以及与该疾病相关的病原体。

背景：犬传染性呼吸道疾病综合症（CIRDC）是一种常见的呼吸道疾病，通常与高密度人群有关：本研究的目的是确定CIRDC最常见的病原体，并确定与诊断相关的风险因素（病原体、环境暴露）：2017 年 4 月至 2018 年 5 月在加拿大进行了一项前瞻性、多诊所、病例对照研究。参与研究的兽医诊所共招募了 110 只狗（74 例病例，36 例对照）。病原体使用呼吸道PCR板进行检测：结果：仅在病例中检测到犬副流感病毒（CPIV）、支气管败血波氏杆菌和犬呼吸道冠状病毒（CRCoV）。根据两个逻辑回归模型，CPIV（OR：14.42；95% CI：2.24 至 ∞）和 CRCoV（OR：8.64；95% CI：1.26 至 ∞）的检测结果与 CIRDC 疾病状态相关。在另一个模型中，接触多犬聚集也增加了诊断为 CIRDC 的几率（OR：3.39；95% CI：1.26 至 9.81）：与其他研究一致，本研究确定 CPIV、CRCoV 和支气管败血波状芽孢杆菌是导致 CIRDC 病例的重要因素。在本研究的条件下，CPIV 和 CRCoV 的检测以及与狗聚集区的接触经统计评估后被确定为对疾病状况有影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Canadian Veterinary Journal-revue Veterinaire Canadienne 农林科学-兽医学

CiteScore

1.20

自引率

10.00%

发文量

177

审稿时长

12-24 weeks

期刊介绍： The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health. A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).