{"title":"Characterisation of pathogenic <i>Leptospira</i> in invasive raccoons (<i>Procyon lotor</i>) in northeast and southwest France.","authors":"Florence Ayral, Elena Harran, Christine Fournier-Chambrillon, Manon Gautrelet, Océane Tourniaire, Alexis Peutot, Karine Groud, Nathan Thenon, Pascal Fournier, Céline Richomme","doi":"10.1017/S095026882400116X","DOIUrl":null,"url":null,"abstract":"<p><p>Leptospirosis is a widespread zoonosis caused by bacteria of the genus <i>Leptospira.</i> Although crucial to mitigate the disease risk, basic epidemiological information is lacking, such as the identities of <i>Leptospira</i> maintenance hosts. The raccoon (<i>Procyon lotor</i>), an alien invasive species in France, could pose a public health risk if it carries pathogenic <i>Leptospira.</i> We investigated the rate and type (selective vs. unselective) of <i>Leptospira</i> carriage in the two main raccoon populations in France. Out of the 141 raccoons collected, seven (5%) tested quantitative PCR positive, targeting <i>lfb1</i> gene, based on kidney, lung, and urine samples. Phylogenetic analysis revealed the presence of three different <i>L. interrogans</i> clusters. The results suggest that raccoons were more likely accidental hosts and made only a limited contribution to <i>Leptospira</i> maintenance.</p>","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Epidemiology and Infection","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/S095026882400116X","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Leptospirosis is a widespread zoonosis caused by bacteria of the genus Leptospira. Although crucial to mitigate the disease risk, basic epidemiological information is lacking, such as the identities of Leptospira maintenance hosts. The raccoon (Procyon lotor), an alien invasive species in France, could pose a public health risk if it carries pathogenic Leptospira. We investigated the rate and type (selective vs. unselective) of Leptospira carriage in the two main raccoon populations in France. Out of the 141 raccoons collected, seven (5%) tested quantitative PCR positive, targeting lfb1 gene, based on kidney, lung, and urine samples. Phylogenetic analysis revealed the presence of three different L. interrogans clusters. The results suggest that raccoons were more likely accidental hosts and made only a limited contribution to Leptospira maintenance.
期刊介绍：
Epidemiology & Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The scope covers the zoonoses, outbreaks, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease, as well as some tropical infections. It has become the key international periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections are of particular value.
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