Impact of weight loss on the risk of urinary incontinence: the role of sex and body type.

IF 2.8 2区医学 Q2 UROLOGY & NEPHROLOGY

World Journal of Urology Pub Date : 2024-11-02 DOI:10.1007/s00345-024-05333-2

Feng Chen, Hao Lin, Yuansi Zhang, Yu Zhang, Maoping Chu, Lulu Pan

{"title":"Impact of weight loss on the risk of urinary incontinence: the role of sex and body type.","authors":"Feng Chen, Hao Lin, Yuansi Zhang, Yu Zhang, Maoping Chu, Lulu Pan","doi":"10.1007/s00345-024-05333-2","DOIUrl":null,"url":null,"abstract":"Introduction: Although weight loss is known to alleviate urinary incontinence (UI) symptoms, the effects of sex and body size on this relationship remain insufficiently explored.Materials and methods: We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2007-2018, comprising 28,161 participants. Weighted logistic regression analysis, fitted curves, and subgroup analysis were used to assess the association between the percentage of weight loss and UI. Propensity score matching (PSM) was performed to account for potential confounding factors.Results: After PSM, multivariate logistic regression showed an inverse relationship between weight loss percentage and UI risk (odds ratio [OR] = 0.97, 95% confidence interval [CI]: 0.94-0.99). Compared with weight loss percentages < 0%, the risk of UI significantly decreased with weight loss percentages > 5% (weight loss percentage 5.1-10%: OR = 0.83, 95% CI: 0.70-1.00; weight loss percentage 10.1-15%: OR = 0.73, 95% CI: 0.55-0.97; weight loss percentage > 15%: OR = 0.52, 95% CI: 0.39-0.70). Furthermore, subgroup analysis indicated that this relationship was more significant in males and non-overweight/non-obese populations.Conclusion: There was an inverse relationship between weight loss percentage and UI risk, with noticeable differences based on sex and body size. However, these findings warrant further investigation.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00345-024-05333-2","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: Although weight loss is known to alleviate urinary incontinence (UI) symptoms, the effects of sex and body size on this relationship remain insufficiently explored.

Materials and methods: We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2007-2018, comprising 28,161 participants. Weighted logistic regression analysis, fitted curves, and subgroup analysis were used to assess the association between the percentage of weight loss and UI. Propensity score matching (PSM) was performed to account for potential confounding factors.

Results: After PSM, multivariate logistic regression showed an inverse relationship between weight loss percentage and UI risk (odds ratio [OR] = 0.97, 95% confidence interval [CI]: 0.94-0.99). Compared with weight loss percentages < 0%, the risk of UI significantly decreased with weight loss percentages > 5% (weight loss percentage 5.1-10%: OR = 0.83, 95% CI: 0.70-1.00; weight loss percentage 10.1-15%: OR = 0.73, 95% CI: 0.55-0.97; weight loss percentage > 15%: OR = 0.52, 95% CI: 0.39-0.70). Furthermore, subgroup analysis indicated that this relationship was more significant in males and non-overweight/non-obese populations.

Conclusion: There was an inverse relationship between weight loss percentage and UI risk, with noticeable differences based on sex and body size. However, these findings warrant further investigation.

查看原文本刊更多论文

减肥对尿失禁风险的影响：性别和体型的作用。

简介：尽管减肥可以减轻尿失禁（UI）症状，但性别和体型对这种关系的影响仍未得到充分探讨：众所周知，减肥可减轻尿失禁（UI）症状，但性别和体型对这一关系的影响仍未得到充分探讨：我们分析了美国国家健康与营养调查（NHANES）2007-2018 年的数据，其中包括 28,161 名参与者。我们采用加权逻辑回归分析、拟合曲线和亚组分析来评估体重减轻百分比与 UI 之间的关系。进行倾向得分匹配（PSM）以考虑潜在的混杂因素：经过倾向得分匹配后，多变量逻辑回归显示，体重减轻百分比与尿失禁风险之间存在反向关系（几率比 [OR] = 0.97，95% 置信区间 [CI]：0.94-0.99）。与体重减轻百分比为 5%（体重减轻百分比为 5.1-10%：OR = 0.83，95% 置信区间 [CI]：0.70-1.00；体重减轻百分比 10.1-15%：OR = 0.73，95% CI：0.55-0.97；体重减轻百分比 > 15%：OR = 0.52，95% CI：0.39-0.70）。此外，亚组分析表明，这种关系在男性和非超重/非肥胖人群中更为显著：结论：减肥百分比与 UI 风险之间存在反向关系，性别和体型差异明显。不过，这些发现值得进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

World Journal of Urology 医学-泌尿学与肾脏学

CiteScore

6.80

自引率

8.80%

发文量

317

审稿时长

4-8 weeks

期刊介绍： The WORLD JOURNAL OF UROLOGY conveys regularly the essential results of urological research and their practical and clinical relevance to a broad audience of urologists in research and clinical practice. In order to guarantee a balanced program, articles are published to reflect the developments in all fields of urology on an internationally advanced level. Each issue treats a main topic in review articles of invited international experts. Free papers are unrelated articles to the main topic.