Muscle characteristics of lower limb in association with physical activity in candidates of total knee arthroplasty with knee osteoarthritis

IF 2.9 Q3 NUTRITION & DIETETICS

Clinical nutrition ESPEN Pub Date : 2024-10-31 DOI:10.1016/j.clnesp.2024.10.160

Gakuto Kitamura , Manabu Nankaku , Takuma Yuri , Takumi Kawano , Shinichi Kuriyama , Shinichiro Nakamura , Kohei Nishitani , Ryosuke Ikeguchi , Shuichi Matsuda

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引用次数: 0

Abstract

Background & aims

This study aimed to clarify the association between physical activity (PA) and physical functions, including both muscle quantity and quality of ankle plantar flexor muscles in patients with knee osteoarthritis (OA).

Methods

A retrospective cohort study was conducted with ninety-two patients with knee OA. PA, leg muscle cross-sectional area (CSA), knee strength, passive knee angle, and knee pain of the affected side were assessed. PA was assessed by the 2011 Knee Society scoring system. CSA of the quadriceps and ankle plantar flexor muscles on the affected side was measured using a computed tomography image. Based on muscle attenuation assessed with Hounsfield units (HU), the muscle quality of targeted muscle was divided into 4 groups as follows: fat tissue (−190 to −30 HU), very low-density muscle (−29 to −1 HU), low-density muscle (0 to 34 HU), and normal-density muscle (NDM, 35 to 100 HU). The CSA was obtained for each of the 4 groups. Univariate and multivariate linear regression analyses were performed to determine the factors associated with PA.

Results

The regression analysis revealed that higher PA was independently associated with the NDM CSA of ankle plantar flexor (β = 0.51), higher knee extension strength (β = 0.28), and milder knee pain (β = −0.29) after adjustment with age, sex, height, weight, and body mass index.

Conclusion

The present study suggested that NDM CSA of ankle plantar flexor in addition to knee function is one of the factors determining the PA in patients with knee OA.

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膝关节骨性关节炎全膝关节置换术候选者下肢肌肉特征与体力活动的关系。

背景与目的：本研究旨在阐明体力活动（PA）与膝关节骨性关节炎（OA）患者身体功能（包括踝关节跖屈肌的肌肉数量和质量）之间的关系：本研究旨在阐明体力活动（PA）与身体功能（包括膝关节骨性关节炎（OA）患者踝关节跖屈肌的肌肉数量和质量）之间的关系：方法：对 92 名膝关节 OA 患者进行了一项回顾性队列研究。方法：对 92 名膝关节 OA 患者进行了回顾性队列研究，评估了受影响一侧的 PA、腿部肌肉横截面积（CSA）、膝关节力量、被动膝关节角度和膝关节疼痛。PA 采用 2011 年膝关节协会评分系统进行评估。患侧股四头肌和踝关节足底屈肌的 CSA 是通过计算机断层扫描图像测量的。根据用 Hounsfield 单位（HU）评估的肌肉衰减情况，将目标肌肉的肌肉质量分为以下 4 组：脂肪组织（-190 至 -30 HU）、极低密度肌肉（-29 至 -1 HU）、低密度肌肉（0 至 34 HU）和正常密度肌肉（NDM，35 至 100 HU）。4 组分别获得 CSA。进行了单变量和多变量线性回归分析，以确定与 PA 相关的因素：回归分析表明，在对年龄、性别、身高、体重和体重指数进行调整后，较高的 PA 与踝关节跖屈的 NDM CSA（β = 0.51）、较高的膝关节伸展力量（β = 0.28）和较轻的膝关节疼痛（β = -0.29）独立相关：本研究表明，除膝关节功能外，踝关节跖屈肌的NDM CSA也是决定膝关节OA患者PA的因素之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical nutrition ESPEN NUTRITION & DIETETICS-

CiteScore

4.90

自引率

3.30%

发文量

512

期刊介绍： Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.