Atypical and giant proliferating pilomatrixoma of the eyelid: a clinicopathological report.

IF 1.7 4区医学 Q3 OPHTHALMOLOGY

BMC Ophthalmology Pub Date : 2024-11-01 DOI:10.1186/s12886-024-03748-4

Mohammad Taher Rajabi, Amirhossein Aghajani, Seyed Mohsen Rafizadeh, Amin Zand, Zohreh Nozarian, Fatemeh Mahmoudi, Mostafa Heidari

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引用次数: 0

Abstract

Background: Pilomatrixoma is an uncommon benign skin neoplasm originating from the hair follicle. Here, we report a rare case of giant and atypical proliferating pilomatrixoma affecting the eyelid.

Case presentation: A 47-year-old male presented with a solitary, giant mass on his left upper eyelid, which had recently shown progressive enlargement. The lesion appeared well-circumscribed with a firm consistency, and measuring 7 × 10 cm. Orbital computed tomography scan revealed no intraorbital extension. The lesion was surgically excised. Histopathological examination identified the mass as an atypical proliferating pilomatrixoma, characterized by a minimal infiltrating margin of the deep plane and focal cytological atypia of the basaloid cells. No recurrence was observed up to one year postoperatively.

Conclusions: Pilomatrixoma is a rare periocular tumor with potential for malignant transformation, often mimicking other lesions in this region. Therefore, any enlarging masses in this area should be excised for histopathological evaluation to rule out malignancy.

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眼睑非典型和巨大增生性皮瘤：临床病理报告。

背景：毛囊瘤是一种不常见的良性皮肤肿瘤，起源于毛囊。在此，我们报告了一例罕见的影响眼睑的巨大非典型增生性皮母细胞瘤：一名 47 岁的男性左上眼睑出现一个单发的巨大肿块，最近肿块逐渐增大。病变呈环状，质地坚硬，大小为 7 × 10 厘米。眼眶计算机断层扫描显示，病灶没有向眶内扩展。手术切除了病灶。组织病理学检查发现，肿块为非典型增生性皮母细胞瘤，其特点是深面浸润边缘极小，基底细胞呈局灶性细胞学不典型性。术后一年未见复发：结论：绒毛膜母细胞瘤是一种罕见的眼周肿瘤，有恶变的可能，通常会模仿该区域的其他病变。因此，该区域任何增大的肿块都应切除并进行组织病理学评估，以排除恶性肿瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Ophthalmology OPHTHALMOLOGY-

CiteScore

3.40

自引率

5.00%

发文量

441

审稿时长

6-12 weeks

期刊介绍： BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.