CAR-ving away OX40L with engineered Tregs

IF 17.6 1区医学 Q1 IMMUNOLOGY

Science Immunology Pub Date : 2024-11-01 DOI:10.1126/sciimmunol.adu0983

Jonathan S. Maltzman

引用次数: 0

Abstract

OX40L–CAR-T_regs show promise for treating autoimmunity and transplantation rejection.

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利用工程化 Tregs 清除 OX40L。

OX40L-CAR-Tregs有望治疗自身免疫和移植排斥反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Science Immunology Immunology and Microbiology-Immunology

CiteScore

32.90

自引率

2.00%

发文量

183

期刊介绍： Science Immunology is a peer-reviewed journal that publishes original research articles in the field of immunology. The journal encourages the submission of research findings from all areas of immunology, including studies on innate and adaptive immunity, immune cell development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology. Additionally, the journal covers research on immune contributions to health and disease, such as host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency. Science Immunology maintains the same high-quality standard as other journals in the Science family and aims to facilitate understanding of the immune system by showcasing innovative advances in immunology research from all organisms and model systems, including humans.