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IF 5.5 1区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chinese Journal of Chemistry Pub Date : 2024-11-01 DOI:10.1002/cjoc.202490232

引用次数: 0

Abstract

Pyridine and piperidine are common structural motifs in natural products and pharmaceutical compounds, underscoring the importance of their synthesis. Our group has developed chiral spiro-bicyclic bisborane catalysts that enable the efficient and highly enantioselective reduction of pyridines to chiral piperidines. Subsequent transformations allow the conversion of the piperidine products into bioactive natural products. More details are discussed in the article by Wang et al. on pages 3088—3092.

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吡啶和哌啶是天然产品和医药化合物中常见的结构基团，这凸显了它们合成的重要性。我们的研究小组开发了手性螺双环双硼烷催化剂，可以高效、高对映选择性地将吡啶还原成手性哌啶。随后的转化过程可将哌啶类产品转化为具有生物活性的天然产品。更多详情请参见 Wang 等人的文章（第 3088-3092 页）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chinese Journal of Chemistry 化学-化学综合

CiteScore

8.80

自引率

14.80%

发文量

422

审稿时长

1.7 months

期刊介绍： The Chinese Journal of Chemistry is an international forum for peer-reviewed original research results in all fields of chemistry. Founded in 1983 under the name Acta Chimica Sinica English Edition and renamed in 1990 as Chinese Journal of Chemistry, the journal publishes a stimulating mixture of Accounts, Full Papers, Notes and Communications in English.