Hemodynamics and vascular oxygenation measured at the forehead during changes in respiration: A SPA-fNIRS study.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Sabino Guglielmini, Elena Wiggli, Felix Scholkmann, Martin Wolf
{"title":"Hemodynamics and vascular oxygenation measured at the forehead during changes in respiration: A SPA-fNIRS study.","authors":"Sabino Guglielmini, Elena Wiggli, Felix Scholkmann, Martin Wolf","doi":"10.1016/j.resp.2024.104364","DOIUrl":null,"url":null,"abstract":"<p><strong>Significance: </strong>Cerebral blood flow is influenced by respiration, primarily through changes in the CO<sub>2</sub> concentration of arterial blood.</p><p><strong>Aim: </strong>The objective of this study was to investigate the effect of changes in arterial CO<sub>2</sub> concentration induced by respiratory changes on oxygenation and hemodynamics in the cerebral and extracerebral tissue layers of the forehead.</p><p><strong>Approach: </strong>We used systemic physiology augmented functional near-infrared spectroscopy (SPA-fNIRS) to assess changes in forehead hemodynamics and oxygenation as well as systemic physiology in 20 healthy subjects. All participants performed two respiratory tasks (breath-holding and hyperventilation).</p><p><strong>Results: </strong>In our SPA-fNIRS study we found that changes in breathing affected hemodynamics and oxygenation in both the extracerebral and cerebral tissue layers of the forehead in characteristic ways, depending on the two respiratory tasks.</p><p><strong>Conclusion: </strong>The results show that extracerebrovascular reactivity (ECVR) exists in parallel with the well-known cerebrovascular reactivity (CVR). CVR and ECVR must be considered when performing fNIRS neuroimaging studies involving changes in respiration.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.resp.2024.104364","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Significance: Cerebral blood flow is influenced by respiration, primarily through changes in the CO2 concentration of arterial blood.

Aim: The objective of this study was to investigate the effect of changes in arterial CO2 concentration induced by respiratory changes on oxygenation and hemodynamics in the cerebral and extracerebral tissue layers of the forehead.

Approach: We used systemic physiology augmented functional near-infrared spectroscopy (SPA-fNIRS) to assess changes in forehead hemodynamics and oxygenation as well as systemic physiology in 20 healthy subjects. All participants performed two respiratory tasks (breath-holding and hyperventilation).

Results: In our SPA-fNIRS study we found that changes in breathing affected hemodynamics and oxygenation in both the extracerebral and cerebral tissue layers of the forehead in characteristic ways, depending on the two respiratory tasks.

Conclusion: The results show that extracerebrovascular reactivity (ECVR) exists in parallel with the well-known cerebrovascular reactivity (CVR). CVR and ECVR must be considered when performing fNIRS neuroimaging studies involving changes in respiration.

呼吸变化时在前额测量血液动力学和血管氧合:SPA-fNIRS 研究。
意义:目的:本研究旨在探讨呼吸变化引起的动脉二氧化碳浓度变化对前额大脑和脑外组织层氧合和血液动力学的影响:方法:我们使用系统生理学增强功能近红外光谱(SPA-fNIRS)来评估 20 名健康受试者前额血液动力学和氧饱和度以及系统生理学的变化。所有受试者都完成了两项呼吸任务(屏气和过度换气):结果:在我们的 SPA-fNIRS 研究中,我们发现呼吸的变化以特有的方式影响着前额脑外组织和脑组织层的血液动力学和氧合,这取决于两种呼吸任务:结果表明,脑外血管反应性(ECVR)与众所周知的脑血管反应性(CVR)同时存在:在进行涉及呼吸变化的 fNIRS 神经成像研究时,必须考虑 CVR 和 ECVR。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信