Is higher physical activity behaviour associated with less subsequent use of any psychotropic medication: Results of a random-effects meta-analysis of prospective cohort studies

IF 2.3 3区医学 Q2 PSYCHIATRY

Mental Health and Physical Activity Pub Date : 2024-10-01 DOI:10.1016/j.mhpa.2024.100645

Sebastian Wolf , Edith Meinzinger , Anna Katharina Frei , Britta Seiffer , Johanna Löchner , Keisuke Takano , Siobhan Scarlett , Rose Anne Kenny , Viviane Derhon , Maria Eduarda Adornes Guimarães , Felipe Barreto Schuch

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引用次数: 0

Abstract

Physical activity is associated with lower risk of incident depression and anxiety disorders. However, there is no meta-analytic evidence on the associations between physical activity levels and the incident use of psychotropic medications. PubMed, Embase, Scopus, Web of Science, PsycINFO, and Cochrane were searched up until March 2024 to identify prospective cohort studies in the general population without age restrictions, with any sample size, and with at least one year of follow-up. Risk of bias was assessed using the Newcastle-Ottawa Scale and a random-effects meta-analysis of adjusted relative risks was performed. Three studies comprising 40,111 participants and 322,521 person-years were included (mean age 53.8, range 18–90 years; 54% women). Relative to people reporting no physical activity, those accumulating any volume of physical activity had 15.0% (95% CI: 0.76, 0.96) lower risk of any subsequent medication use. Heterogeneity was moderate and not significant (I² = 33.6%). The current meta-analysis demonstrated that people with higher physical activity levels are at lower risk of subsequent use of psychotropic medication. However, the evidence is based on a small number of studies (n = 3), highlighting the need for high-quality longitudinal studies.

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较多的体育锻炼行为是否与随后较少使用任何精神药物有关：前瞻性队列研究的随机效应荟萃分析结果

体育锻炼与抑郁症和焦虑症的发病风险降低有关。然而，目前还没有荟萃分析证据表明体育锻炼水平与精神药物的使用之间存在关联。我们对 PubMed、Embase、Scopus、Web of Science、PsycINFO 和 Cochrane 进行了检索，以确定截至 2024 年 3 月在普通人群中进行的前瞻性队列研究，这些研究不受年龄限制，样本大小不限，随访时间至少一年。使用纽卡斯尔-渥太华量表对偏倚风险进行了评估，并对调整后的相对风险进行了随机效应荟萃分析。三项研究共纳入 40,111 名参与者和 322,521 人年（平均年龄为 53.8 岁，年龄范围为 18-90 岁；54% 为女性）。与未进行体育锻炼的人相比，积累任何体育锻炼量的人随后使用任何药物的风险降低了 15.0% (95% CI: 0.76, 0.96)。异质性适中且不显著（I2 = 33.6%）。目前的荟萃分析表明，体育锻炼水平较高的人随后使用精神药物的风险较低。然而，这些证据仅基于少量研究（n = 3），因此需要进行高质量的纵向研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mental Health and Physical Activity PSYCHIATRY-

CiteScore

6.70

自引率

6.40%

发文量

审稿时长

32 days

期刊介绍： The aims of Mental Health and Physical Activity will be: (1) to foster the inter-disciplinary development and understanding of the mental health and physical activity field; (2) to develop research designs and methods to advance our understanding; (3) to promote the publication of high quality research on the effects of physical activity (interventions and a single session) on a wide range of dimensions of mental health and psychological well-being (eg, depression, anxiety and stress responses, mood, cognitive functioning and neurological disorders, such as dementia, self-esteem and related constructs, psychological aspects of quality of life among people with physical and mental illness, sleep, addictive disorders, eating disorders), from both efficacy and effectiveness trials;