Extreme bradycardia in a case of benzodiazepine intoxication in a “body stuffer” (Bradicardia extrema en un caso de intoxicación por benzodiacepinas en un “body stuffer”)

Q1 Environmental Science
Jaime La Rota , Camilo Nemeguén , Laura Narváez , Jose Motta , Juan Calderón
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Abstract

Transport intoxication in the form of body stuffing, a dangerous practice involving the ingestion or insertion of psychoactive substances into the body to evade detection during drug trafficking, represents a major medical problem that requires immediate attention in the emergency department. Unlike body packing, where substances are encapsulated and swallowed for later extraction, body stuffing involves direct ingestion without wrapping, which greatly increases the risk of serious intoxication and even death. Benzodiazepines, due to their high demand on the black market, are among the most common drugs used in body stuffing. The management of this type of poisoning in the emergency department presents a significant clinical challenge due to the variability in clinical presentation, which can range from drowsiness and confusion to respiratory depression and coma.Rapid and accurate assessment is critical for effective management.The initial focus is on patient stabilization and life support as needed, which may include administration of naloxone to reverse opioid effects, mechanical ventilation for respiratory depression, and management of seizures if they occur.An appropriate approach in the emergency department is crucial to improve the prognosis and quality of life of patients affected by this type of poisoning. Timely intervention and expert management can prevent serious complications and even death. We present the case of a patient with benzodiazepine intoxication with an atypical presentation due to clonazepam transport with bradycardia and its management in an institution in Bogotá-Colombia.
在一例苯并二氮杂卓中毒的 "身体填充物 "中出现极度心动过缓(Bradicardia extrema en un caso de intoxicación por benzodiacepinas en un "body stuffer")
在贩毒过程中,为逃避侦查而将精神药物摄入或塞入体内的危险做法是一种需要急诊科立即关注的重大医疗问题。与体内包裹不同的是,体内塞药是将药物封装后吞咽,以便日后提取,而体内塞药则是不经包裹直接摄入,这大大增加了严重中毒甚至死亡的风险。苯二氮卓类药物由于在黑市上需求量大,是填尸中最常用的药物之一。由于临床表现多变,从嗜睡和意识模糊到呼吸抑制和昏迷,急诊科对此类中毒的处理是一项重大的临床挑战。及时干预和专业治疗可以防止严重并发症甚至死亡的发生。我们介绍了哥伦比亚波哥大一家医疗机构收治的一例苯二氮卓类药物中毒患者,该患者因服用氯硝西泮导致心动过缓,表现不典型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Toxicology Reports
Toxicology Reports Environmental Science-Health, Toxicology and Mutagenesis
CiteScore
7.60
自引率
0.00%
发文量
228
审稿时长
11 weeks
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