Mechanisms of action for FDA-approved drugs targeting breast cancer

Abstract

Breast cancer treatment encompasses a diverse range of therapeutic strategies targeting specific molecular pathways crucial for tumor growth and progression. Several exciting advancements are likely to shape the future of breast cancer treatment. Understanding the mechanisms by which FDA-approved drugs exert their effects is crucial for optimizing treatment strategies and improving patient outcomes. In this review, we aim to categorize FDA-approved drugs for breast cancer treatment based on their distinct modes of action or mechanisms These mechanisms cover several activities, such as blocking particular enzymes that are essential for the synthesis of hormones, interfering with cellular functions that are necessary for the growth and spread of tumors, altering signaling pathways that are critical for the survival of cancer cells, and taking advantage of weaknesses in DNA repair mechanisms that are specific to them. In order to effectively battle this heterogeneous disease, a customized and all-encompassing therapeutic approach is required. This multifaceted approach highlights the crucial role of therapeutic approaches and synergistic treatment modalities in maximizing efficacy and improving prognosis for individuals with breast cancer.