AI's role in revolutionizing personalized medicine by reshaping pharmacogenomics and drug therapy

Hamed Taherdoost , Alireza Ghofrani
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Abstract

This paper examines the transformative impact of artificial intelligence (AI) on pharmacogenomics, signaling a paradigm shift in personalized medicine. With a focus on enhancing drug response prediction and treatment optimization, AI, particularly machine learning and deep learning algorithms, navigates the complexity of genomic data. By elucidating intricate relationships between genetic factors and drug responses, AI augments the identification of genetic markers and contributes to the development of comprehensive models. The review emphasizes AI's role in guiding treatment decisions, minimizing adverse reactions, and optimizing drug dosages in clinical settings. Ethical considerations, challenges, and future directions are also discussed. This work underscores the synergy of AI and pharmacogenomics, offering a more effective and patient-centric approach to drug therapy, marking a significant advancement in the field of personalized medicine.
通过重塑药物基因组学和药物疗法,人工智能在个性化医疗变革中的作用
本文探讨了人工智能(AI)对药物基因组学的变革性影响,这标志着个性化医疗模式的转变。人工智能,尤其是机器学习和深度学习算法,以加强药物反应预测和治疗优化为重点,在复杂的基因组数据中游刃有余。通过阐明遗传因素与药物反应之间错综复杂的关系,人工智能增强了遗传标记的识别能力,并促进了综合模型的开发。综述强调了人工智能在指导治疗决策、减少不良反应和优化临床用药剂量方面的作用。此外,还讨论了伦理考虑因素、挑战和未来方向。这项工作强调了人工智能和药物基因组学的协同作用,为药物治疗提供了更有效和以患者为中心的方法,标志着个性化医疗领域的重大进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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