{"title":"Recent advances in multifunctional nanomaterials enhanced immunochromatographic assays","authors":"Yanna Shao , Sicheng Xiong , Mingzhu Huang , Bin Liu , Zehao Huang , Dong Xu , Xuelan Chen , Yonghua Xiong","doi":"10.1016/j.trac.2024.118013","DOIUrl":null,"url":null,"abstract":"<div><div>With continuous advancements in material science, nanomaterials with excellent multifunctional properties resulting from synergistic or complementary effects as an alternative to traditional gold nanoparticles (AuNPs) have emerged as a research hotspot to improve the analytical performance of immunochromatographic assay (ICA). This review first discusses various design strategies of multifunctional nanomaterials through the rational integration of different functional components into a single nanocomposite. Then, novel dimensional strategies to enhance the analytical performance of ICA, including sample pretreatment, regulation of fluid dynamics, multi-signal approaches and catalytic amplification of nanomaterials, are also described. Furthermore, this review provides an overview of the challenges encountered in the engineering of multifunctional nanomaterials-based ICA. Finally, the future trends of ICA strips based on these advanced materials are forecasted. Overall, this review serves as an important reference for understanding the current status of multifunctional nanomaterials and offers insights into the development of the next generation of ICA platforms.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"181 ","pages":"Article 118013"},"PeriodicalIF":11.8000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993624004965","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
With continuous advancements in material science, nanomaterials with excellent multifunctional properties resulting from synergistic or complementary effects as an alternative to traditional gold nanoparticles (AuNPs) have emerged as a research hotspot to improve the analytical performance of immunochromatographic assay (ICA). This review first discusses various design strategies of multifunctional nanomaterials through the rational integration of different functional components into a single nanocomposite. Then, novel dimensional strategies to enhance the analytical performance of ICA, including sample pretreatment, regulation of fluid dynamics, multi-signal approaches and catalytic amplification of nanomaterials, are also described. Furthermore, this review provides an overview of the challenges encountered in the engineering of multifunctional nanomaterials-based ICA. Finally, the future trends of ICA strips based on these advanced materials are forecasted. Overall, this review serves as an important reference for understanding the current status of multifunctional nanomaterials and offers insights into the development of the next generation of ICA platforms.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.