Donor clinical characteristics and impacts on transfusion recipient outcomes

IF 1.4 4区医学 Q4 HEMATOLOGY

Transfusion and Apheresis Science Pub Date : 2024-10-15 DOI:10.1016/j.transci.2024.104012

Shuoyan Ning , Michelle Zeller , Nancy M. Heddle

引用次数: 0

Abstract

Clinical characteristics of blood donors may affect short- and long-term outcomes of transfusion recipients. The impact of donor sex and age on recipient outcomes have not yielded consistent results in observational studies. One recently published randomized controlled trial (iTADS) addressing the impact of donor sex on recipient outcomes noted no differences between a female versus male transfusion strategy; a second Canadian multicenter trial has just been funded. Other donor characteristics - including pregnancy history, smoking status, obesity, and chronic illnesses - remain incompletely explored. More robust clinical studies with vein-to-vein capabilities are needed to understand the complex interplay between donors and recipients.

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捐献者的临床特征及其对输血受体结果的影响。

献血者的临床特征可能会影响输血受者的短期和长期治疗效果。关于献血者性别和年龄对受血者预后的影响，观察性研究的结果并不一致。最近发表的一项随机对照试验（iTADS）探讨了献血者性别对受血者预后的影响，发现女性与男性输血策略之间没有差异；第二项加拿大多中心试验刚刚获得资助。其他捐献者特征--包括怀孕史、吸烟状况、肥胖和慢性疾病--仍未得到充分探讨。要了解供体和受体之间复杂的相互作用，还需要更多具有静脉对静脉功能的临床研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transfusion and Apheresis Science 医学-血液学

CiteScore

3.60

自引率

5.30%

发文量

181

审稿时长

42 days

期刊介绍： Transfusion and Apheresis Science brings comprehensive and up-to-date information to physicians and health care professionals involved in the rapidly changing fields of transfusion medicine, hemostasis and apheresis. The journal presents original articles relating to scientific and clinical studies in the areas of immunohematology, transfusion practice, bleeding and thrombotic disorders and both therapeutic and donor apheresis including hematopoietic stem cells. Topics covered include the collection and processing of blood, compatibility testing and guidelines for the use of blood products, as well as screening for and transmission of blood-borne diseases. All areas of apheresis - therapeutic and collection - are also addressed. We would like to specifically encourage allied health professionals in this area to submit manuscripts that relate to improved patient and donor care, technical aspects and educational issues. Transfusion and Apheresis Science features a "Theme" section which includes, in each issue, a group of papers designed to review a specific topic of current importance in transfusion and hemostasis for the discussion of topical issues specific to apheresis and focuses on the operators'' viewpoint. Another section is "What''s Happening" which provides informal reporting of activities in the field. In addition, brief case reports and Letters to the Editor, as well as reviews of meetings and events of general interest, and a listing of recent patents make the journal a complete source of information for practitioners of transfusion, hemostasis and apheresis science. Immediate dissemination of important information is ensured by the commitment of Transfusion and Apheresis Science to rapid publication of both symposia and submitted papers.