Cardiovascular magnetic resonance semi-automated threshold-based post-processing of right ventricular volumes in repaired tetralogy of Fallot.

IF 9.7 1区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiologia Medica Pub Date : 2024-10-30 DOI:10.1007/s11547-024-01908-6

Lara Tondi, Stefano Figliozzi, Sara Boveri, Francesco Sturla, Giulia Pasqualin, Antonia Camporeale, Giandomenico Disabato, Andrea Attanasio, Gianpaolo Carrafiello, Pietro Spagnolo, Massimo Lombardi

{"title":"Cardiovascular magnetic resonance semi-automated threshold-based post-processing of right ventricular volumes in repaired tetralogy of Fallot.","authors":"Lara Tondi, Stefano Figliozzi, Sara Boveri, Francesco Sturla, Giulia Pasqualin, Antonia Camporeale, Giandomenico Disabato, Andrea Attanasio, Gianpaolo Carrafiello, Pietro Spagnolo, Massimo Lombardi","doi":"10.1007/s11547-024-01908-6","DOIUrl":null,"url":null,"abstract":"Background: Cardiovascular magnetic resonance (CMR) is the gold-standard to estimate right ventricular (RV) volumes, which are key for clinical management of patients with repaired tetralogy of Fallot (rTOF). Semi-automated threshold-based methods (SAT) have been proposed for CMR post-processing as alternatives to fully manual standard tracing. We investigated the impact of SAT on RV analysis using different thresholds in rTOF patients.Methods: RV volumes and mass were estimated using SAT and standard fully manual tracing methods in rTOF patients. Two threshold levels were set for SAT, i.e., default 50 (SAT-50) and 30 (SAT-30). RV stroke volumes (SV) were compared to main pulmonary artery forward flow (MPA-FF). Post-processing time, intra- and interobserver variabilities were compared across methods.Results: Sixty-two CMRs of rTOF patients were analyzed. Compared to the standard fully manual tracing, no significant differences in RV mass, volumes and ejection fraction were observed using SAT-30, whereas SAT-50 significantly underestimated RV end-diastolic-volume index (EDVi) by 10.4% (mean difference of - 11.8 ± 6.2 ml/m2, p 0.03) and overestimated RV mass index by 21.8% (mean difference of 14.2 ± 11.9 g/m2, p 0.002). Compared to MPA-FF, RVSV by standard fully manual method and SAT-30 showed minor biases, respectively, 0.03 ml/m2 and 0.7 ml/m2, while SAT-50 underestimated RVSV by 6.86 ml/m2 (p < 0.001). In six patients, the degree of RV EDVi underestimation by SAT-50 determined a change of category from dilated to non-dilated RV. Intra- and interobserver variabilities were good to excellent for all methods. Post-processing duration was shorter for SAT compared to standard manual segmentation (5.5 ± 1.7 min vs. 19.5 ± 4.4 min, p < 0.001).Conclusion: CMR SAT-30 post-processing is a precise, accurate and time-saving method for biventricular assessment of volumes, ejection fraction and mass in rTOF.","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":null,"pages":null},"PeriodicalIF":9.7000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiologia Medica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11547-024-01908-6","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Cardiovascular magnetic resonance (CMR) is the gold-standard to estimate right ventricular (RV) volumes, which are key for clinical management of patients with repaired tetralogy of Fallot (rTOF). Semi-automated threshold-based methods (SAT) have been proposed for CMR post-processing as alternatives to fully manual standard tracing. We investigated the impact of SAT on RV analysis using different thresholds in rTOF patients.

Methods: RV volumes and mass were estimated using SAT and standard fully manual tracing methods in rTOF patients. Two threshold levels were set for SAT, i.e., default 50 (SAT-50) and 30 (SAT-30). RV stroke volumes (SV) were compared to main pulmonary artery forward flow (MPA-FF). Post-processing time, intra- and interobserver variabilities were compared across methods.

Results: Sixty-two CMRs of rTOF patients were analyzed. Compared to the standard fully manual tracing, no significant differences in RV mass, volumes and ejection fraction were observed using SAT-30, whereas SAT-50 significantly underestimated RV end-diastolic-volume index (EDVi) by 10.4% (mean difference of - 11.8 ± 6.2 ml/m², p 0.03) and overestimated RV mass index by 21.8% (mean difference of 14.2 ± 11.9 g/m², p 0.002). Compared to MPA-FF, RVSV by standard fully manual method and SAT-30 showed minor biases, respectively, 0.03 ml/m² and 0.7 ml/m², while SAT-50 underestimated RVSV by 6.86 ml/m² (p < 0.001). In six patients, the degree of RV EDVi underestimation by SAT-50 determined a change of category from dilated to non-dilated RV. Intra- and interobserver variabilities were good to excellent for all methods. Post-processing duration was shorter for SAT compared to standard manual segmentation (5.5 ± 1.7 min vs. 19.5 ± 4.4 min, p < 0.001).

Conclusion: CMR SAT-30 post-processing is a precise, accurate and time-saving method for biventricular assessment of volumes, ejection fraction and mass in rTOF.

查看原文本刊更多论文

心血管磁共振半自动阈值法洛四联症修复后右心室容积后处理。

背景：心血管磁共振（CMR）是估算右心室容积的黄金标准，而右心室容积是法洛氏四联症（rTOF）修复患者临床管理的关键。有人提出了基于阈值的半自动方法（SAT）用于 CMR 后处理，以替代全手工标准描记。我们研究了 SAT 使用不同阈值对 rTOF 患者 RV 分析的影响：方法：使用 SAT 和标准全手动描记方法估算 rTOF 患者的 RV 容量和质量。为 SAT 设定了两个阈值水平，即默认值 50（SAT-50）和 30（SAT-30）。将 RV 搏出量（SV）与主肺动脉前向血流（MPA-FF）进行比较。比较了不同方法的后处理时间、观察者内部和观察者之间的差异：对 62 例 rTOF 患者的 CMR 进行了分析。与标准的全手动描记相比，使用 SAT-30 观察到的 RV 质量、容积和射血分数无明显差异，而 SAT-50 则明显低估了 RV 舒张末期容积指数（EDVi）10.4%（平均差异为 - 11.8 ± 6.2 ml/m2，P 0.03），高估了 RV 质量指数 21.8%（平均差异为 14.2 ± 11.9 g/m2，P 0.002）。与 MPA-FF 相比，标准全手工方法和 SAT-30 的 RVSV 偏差较小，分别为 0.03 ml/m2 和 0.7 ml/m2，而 SAT-50 则低估了 RVSV 6.86 ml/m2（p 结论：MPA-FF 和 SAT-30 的 RVSV 偏差较小，分别为 0.03 ml/m2 和 0.7 ml/m2：CMR SAT-30 后处理是在 rTOF 中评估双心室容积、射血分数和质量的一种精确、准确和省时的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Radiologia Medica 医学-核医学

CiteScore

14.10

自引率

7.90%

发文量

133

审稿时长

4-8 weeks

期刊介绍： Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.