Incidence of high blood pressure among Kenyan adults living with HIV: a longitudinal cohort analysis from 2004-2023.

IF 3.4 2区 医学 Q3 IMMUNOLOGY
AIDS Pub Date : 2024-10-29 DOI:10.1097/QAD.0000000000004050
Kara Suvada, Erica Kocher, Nazha Diwan, Andrew Nagy, Mary Nderitu, Charles Kibaara, Richard Ngomoa, Tony J Cagle, Jacob Kariukii, Kristin M Wall, Ludivine Brunissen, Shashank Ramireddy, Leslie C M Johnson, Michael H Chung, Mohammed K Ali
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Abstract

Objective: People with HIV (PWH) face a heightened risk of cardiovascular diseases, partly due to increased high blood pressure risk. This study assessed high blood pressure burden (i.e., incidence, prevalence) among PWH in Kenya over time.

Design: Longitudinal, open cohort study.

Methods: We estimated the incidence and prevalence of high blood pressure in a large sample of Kenyans with HIV from the Coptic Hope Center using electronic medical records from 2004-2023. We defined incident high blood pressure as first visit after baseline at which each patient had a systolic blood pressure ≥ 140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg.

Results: Our sample included 38,709 PWH seeking care at Coptic Hope Center clinics in Kenya (2004-2023). Nearly 40% of patients had high blood pressure at first visit. Among the 60% of patients initially normotensive, almost 40% developed high blood pressure within 20 years. The yearly prevalence of high blood pressure ranged from 8-58%. Average SBP was higher among patients who had their first visit from 2019-2023 compared to those visiting in the early 2000 s and 2010 s.

Conclusions: Our findings reveal a high and rising burden of high blood pressure among PWH in a large, faith-based health system in Kenya. This underscores the need for stronger integration of care for individuals with concurrent HIV, high blood pressure, and other non-communicable diseases. Current systems are insufficient for achieving blood pressure control among PWH. Further research and funding for efforts to address HIV and NCD care in Kenya are warranted.

肯尼亚成年艾滋病毒感染者的高血压发病率:2004-2023 年纵向队列分析。
目的:艾滋病病毒感染者(PWH)罹患心血管疾病的风险增加,部分原因是高血压风险增加。本研究评估了肯尼亚艾滋病感染者随时间变化的高血压负担(即发病率和流行率):设计:纵向、开放式队列研究:我们利用 2004-2023 年间的电子病历,对科普特希望中心的肯尼亚艾滋病感染者大样本中的高血压发病率和患病率进行了估算。我们将基线后首次就诊时每位患者的收缩压≥140 mmHg和/或舒张压≥90 mmHg定义为高血压事件:我们的样本包括在肯尼亚科普特希望中心诊所就诊的 38 709 名残疾人(2004-2023 年)。近 40% 的患者在首次就诊时患有高血压。在 60% 最初血压正常的患者中,近 40% 在 20 年内发展为高血压。高血压的年患病率为 8%-58%。与2000年代初和2010年代就诊的患者相比,2019-2023年首次就诊的患者平均SBP更高:我们的研究结果表明,在肯尼亚一个以信仰为基础的大型医疗系统中,公共卫生人员的高血压负担很高,而且还在不断上升。这突出表明,需要加强对同时患有艾滋病、高血压和其他非传染性疾病的患者的综合治疗。目前的系统不足以实现对艾滋病感染者的血压控制。有必要进一步开展研究并提供资金,以解决肯尼亚的艾滋病和非传染性疾病护理问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
AIDS
AIDS 医学-病毒学
CiteScore
5.90
自引率
5.30%
发文量
478
审稿时长
3 months
期刊介绍: ​​​​​​​​​​​​​​​​​Publishing the very latest ground breaking research on HIV and AIDS. Read by all the top clinicians and researchers, AIDS has the highest impact of all AIDS-related journals. With 18 issues per year, AIDS guarantees the authoritative presentation of significant advances. The Editors, themselves noted international experts who know the demands of your work, are committed to making AIDS the most distinguished and innovative journal in the field. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.
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