Nanoengineering Spikey Surfaces: Investigation of Reversible Organizational Control of Surface-Tethered Polypeptide Brushes.

IF 3.7 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir Pub Date : 2024-11-12 Epub Date: 2024-10-30 DOI:10.1021/acs.langmuir.4c03345

Yuming Huang, Hyunseok Kim, Luis Adrián Padilla Salas, Warren R Zipfel, Su-Mi Hur, Christopher K Ober

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Abstract

Nature serves as an important source of inspiration for the innovation and development of micro- and nanostructures for advanced functional surfaces and substrates. One example used in nature is a spikey surface ranging from micrometer-sized spikes on pollen grains down to the nanometer-scale protein spikes found on viruses. This study explored the realization of such highly textured surfaces via the nanoengineering of self-assembled poly(γ-benzyl-l-glutamate) "nanospikes", exploiting solvent-induced chain organization, controlled surface chemical functionality, and enhanced stability in the form of polymer brushes. The reversible solvent-responsive behavior of these polymer chains and the aggregation behavior of the chain-ends were investigated via fluorescence characterization and studied through molecular simulations. Vapor-based solvent treatments were developed for orientation control with in situ analysis to understand film response and brush organizational behavior under different selected conditions. The effect of sub-100 nm nanopatterning on surface morphology and chain organization was examined via an integrated approach of experimental and computational studies. The methodologies established in this study present opportunities for engineering sophisticated nanoscale spikey surfaces with high customizability by means of nanolithography combined with solvent-assisted treatments.

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穗状表面纳米工程：研究表面系链多肽刷的可逆组织控制。

大自然是创新和开发用于先进功能表面和基底的微纳米结构的重要灵感来源。自然界中的一个例子就是尖刺表面，从花粉粒上的微米级尖刺到病毒上的纳米级蛋白质尖刺，不一而足。本研究探索了通过自组装聚（γ-苄基-l-谷氨酸）"纳米尖峰 "的纳米工程，利用溶剂诱导的链组织、可控的表面化学功能和聚合物刷形式的增强稳定性，实现这种高纹理表面。通过荧光表征和分子模拟研究了这些聚合物链的可逆溶剂响应行为和链端聚集行为。开发了用于取向控制的气基溶剂处理方法，并进行了现场分析，以了解不同选定条件下的薄膜响应和刷组织行为。通过实验和计算研究的综合方法，研究了 100 纳米以下的纳米图案对表面形态和链组织的影响。本研究中建立的方法为通过纳米光刻技术结合溶剂辅助处理来设计具有高度可定制性的复杂纳米级尖刺表面提供了机会。

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来源期刊

Langmuir 化学-材料科学：综合

CiteScore

6.50

自引率

10.30%

发文量

1464

审稿时长

2.1 months

期刊介绍： Langmuir is an interdisciplinary journal publishing articles in the following subject categories: Colloids: surfactants and self-assembly, dispersions, emulsions, foams Interfaces: adsorption, reactions, films, forces Biological Interfaces: biocolloids, biomolecular and biomimetic materials Materials: nano- and mesostructured materials, polymers, gels, liquid crystals Electrochemistry: interfacial charge transfer, charge transport, electrocatalysis, electrokinetic phenomena, bioelectrochemistry Devices and Applications: sensors, fluidics, patterning, catalysis, photonic crystals However, when high-impact, original work is submitted that does not fit within the above categories, decisions to accept or decline such papers will be based on one criteria: What Would Irving Do? Langmuir ranks #2 in citations out of 136 journals in the category of Physical Chemistry with 113,157 total citations. The journal received an Impact Factor of 4.384*. This journal is also indexed in the categories of Materials Science (ranked #1) and Multidisciplinary Chemistry (ranked #5).