A 3D Bioprinted Cortical Organoid Platform for Modeling Human Brain Development (Adv. Healthcare Mater. 27/2024)

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2024-10-28 DOI:10.1002/adhm.202470173

Melissa A. Cadena, Anson Sing, Kylie Taylor, Linqi Jin, Liqun Ning, Mehdi Salar Amoli, Yamini Singh, Samantha N. Lanjewar, Martin L. Tomov, Vahid Serpooshan, Steven A. Sloan

引用次数: 0

Abstract

3D Bioprinting

The cover of the article 2401603 by Vahid Serpooshan, Steven A. Sloan, and co-workers conceptualizes the attraction of endothelial roads towards a spherical city, where new vascularization invites life and greenery that is otherwise lacking. This work utilizes 3D bioprinting of gelatin methacrylate scaffolds to support the growth and differentiation of human brain organoids. The custom and tunable architecture of bioprinted scaffolds allows for intricate features like the introduction of endothelialized channels that migrate towards and infiltrate embedded organoids. Cover art by Flyazure.

Abstract Image

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用于模拟人类大脑发育的三维生物打印皮质类器官平台（Adv.）

三维生物打印Vahid Serpooshan、Steven A. Sloan 及合作者撰写的文章 2401603 的封面构思了内皮道路对球形城市的吸引力，新的血管化为这座城市带来了生命和绿色。这项研究利用甲基丙烯酸明胶支架的三维生物打印技术来支持人脑器官组织的生长和分化。生物打印支架的定制和可调结构可实现复杂的功能，如引入内皮化通道，使其向嵌入的器官组织迁移并浸润。封面设计：Flyazure。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.