Improvement of Therapeutic Effect via Inducing Non-Apoptotic Cell Death Using mRNA-Protection Nanocage (Adv. Healthcare Mater. 27/2024)

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2024-10-28 DOI:10.1002/adhm.202470172

Seoyoung Kim, Seongchan Kim, Sojin Kim, Nan-Ee Lee, Soo-Hwan Lee, Hyunkyung Kim, Hyojin Lee

引用次数: 0

Abstract

mRNA-Protective Nanocage

Necroptosis-induced mRNA expression with nanocage led to significant tumor suppression and immune cell infiltration in vivo model, highlighting the potential of mRNA and nanotechnology-based therapeutics in various diseases including cancer with drug resistance. More details can be found in article 2400240 by Hyunkyung Kim, Hyojin Lee, and co-workers.

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利用 mRNA 保护纳米笼诱导细胞非凋亡以提高疗效（Adv. Healthcare Mater. 27/2024）

mRNA 保护性纳米笼纳米笼诱导的 mRNA 表达在体内模型中导致了显著的肿瘤抑制和免疫细胞浸润，凸显了基于 mRNA 和纳米技术的疗法在包括癌症耐药性在内的各种疾病中的潜力。更多详情请见 Hyunkyung Kim、Hyojin Lee 及合作者撰写的文章 2400240。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.