Siyuan Li, Feng Wang, Yang Chen, Wanrui Shi, Dashuai Liu, Mingyang Lv, Bin Zhao, Yi Liu, Hao Zhang
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引用次数: 0
Abstract
Aggregated lysine mimics antimicrobial peptides (AMPs) by disrupting bacterial membranes, interfering with metabolism, and inhibiting protein synthesis. With Fe3+ hydrolysis, lysine coordination, and ultrasmall Au nanoparticle deposition, FeOOH@Fe-Lysine@Au shows AMP-like antibacterial activity and reactive oxygen species generation, providing an effective approach for cariogenic biofilm microenvironment-activated caries treatment (e578).