Targeted drug delivery via intrathecal pain pump for the treatment of malignant pain

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Dr. George Zlotchenko MD , Dr. Thor Johnson MD, PhD , Katherine Kelson BA
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引用次数: 0

Abstract

Cancer patients experience pain at significant rates but are often undertreated—it is estimated that less than 1% of eligible cancer pain patients receive appropriate targeted drug delivery to address their pain. Cancer pain is often managed with systemic opioid treatment; however, this approach is limited in treating pain adequately and carries significant side effect risk profiles. Successful treatment of pain is closely tied to better oncologic outcomes as well as better measures on assessments of quality of life for cancer patients. Placement of intrathecal pain pumps represent a safe and effective way to manage pain in cancer patients. We describe the process of placing intrathecal pain pumps in an interventional radiology suite. This method of pump placement represents a minimally invasive approach to long term and continuous pain relief. Intrathecal pain pumps help maximize pain control for patients experiencing refractory pain due to disease process or treatments associated with malignancy.
通过鞘内止痛泵靶向给药治疗恶性疼痛
据估计,在符合条件的癌症疼痛患者中,只有不到 1%的患者接受了适当的靶向药物治疗。癌症疼痛通常采用全身性阿片类药物治疗;然而,这种方法在充分治疗疼痛方面存在局限性,而且副作用风险很大。成功的疼痛治疗与更好的肿瘤治疗效果以及更好的癌症患者生活质量评估密切相关。放置鞘内镇痛泵是控制癌症患者疼痛的一种安全有效的方法。我们描述了在介入放射科手术室放置鞘内镇痛泵的过程。这种泵植入方法是一种长期、持续缓解疼痛的微创方法。鞘内镇痛泵有助于最大限度地控制因疾病过程或恶性肿瘤相关治疗而引起的难治性疼痛患者的疼痛。
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来源期刊
Techniques in Vascular and Interventional Radiology
Techniques in Vascular and Interventional Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.70
自引率
0.00%
发文量
47
期刊介绍: Interventional radiology is an area of clinical diagnosis and management that is highly technique-oriented. Therefore, the format of this quarterly journal, which combines the visual impact of an atlas with the currency of a journal, lends itself perfectly to presenting the topics. Each issue is guest edited by a leader in the field and is focused on a single clinical technique or problem. The presentation is enhanced by superb illustrations and descriptive narrative outlining the steps of a particular procedure. Interventional radiologists, neuroradiologists, vascular surgeons and neurosurgeons will find this a useful addition to the clinical literature.
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