Marchiafava-Bignami disease with typical imaging findings: A case report

Q4 Medicine

Radiology Case Reports Pub Date : 2024-10-24 DOI:10.1016/j.radcr.2024.09.132

Noura Boukricha MD, Wadii Bnouhanna PhD, Mounia Rahmani PhD, Maria Benabdeljlil PhD, Saadia Aidi PhD

引用次数: 0

Abstract

Marchiafava-Bignami disease is a rare neurological condition characterized by necrosis and demyelination of the corpus callosum, typically associated with chronic alcoholism and/or malnutrition. The clinical manifestations of Marchiafava-Bignami disease are diverse and often nonspecific. Diagnosis of Marchiafava-Bignami disease relies on magnetic resonance imaging findings, which reveal significant and symmetrical involvement of the corpus callosum. We report the case of a 48-year-old man with chronic alcoholism who has been experiencing symptoms of confusion, stupor, difficulties in using and manipulating objects, and balance disorders for the past 10 days. Brain magnetic resonance imaging revealed diffuse and complete involvement of the corpus callosum, characteristic of a severe form of Marchiafava-Bignami disease.

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具有典型影像学发现的 Marchiafava-Bignami 病：病例报告

马奇亚法瓦-比尼亚米病是一种罕见的神经系统疾病，以胼胝体坏死和脱髓鞘为特征，通常与慢性酒精中毒和/或营养不良有关。马奇亚法瓦-比尼亚米病的临床表现多种多样，通常没有特异性。马奇亚法瓦-比尼亚米病的诊断依赖于磁共振成像结果，该结果显示胼胝体明显对称受累。我们报告了一例 48 岁男性患者的病例，该患者长期酗酒，在过去 10 天内出现意识模糊、昏迷、使用和操作物体困难以及平衡障碍等症状。脑磁共振成像显示，胼胝体弥漫性完全受累，这是严重的马奇亚法瓦-比尼亚米病的特征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

1.10

自引率

0.00%

发文量

1074

审稿时长

30 days

期刊介绍： The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.